Korean J Med.  2011 May;80(5):620-624.

A Case of Adult Onset Still's Disease Presented with Acute Febrile Hepatitis

• Lee SJ
• Chough HS
• Cho MK
• Na JS
• Kim HS
• Kim MW

Abstract

Adult-onset Still's Disease (AOSD) is a rare, immune-mediated, multisystem inflammatory disorder characterized by quotidian spiking fevers, an evanescent rash, arthritis, lymphadenopathy, splenomegaly, a sore throat, leukocytosis, and liver dysfunction. Its clinical manifestations are very diverse, from relatively mild symptoms to severe complications, such as disseminated intravascular coagulation, cardiac tamponade, acute respiratory distress syndrome, hemophagocytic syndrome, and hepatic failure. Hepatic failure is an extremely rare complication that could lead to death. Therefore, early diagnosis and treatment are important. We report a case of adult-onset Still's disease with acute febrile hepatitis.

Keyword

Hepatitis; Adult-onset Still's disease

MeSH Terms

Adult
Arthritis
Cardiac Tamponade
Disseminated Intravascular Coagulation
Early Diagnosis
Exanthema
Fever
Hepatitis
Humans
Leukocytosis
Liver Diseases
Liver Failure
Lymphatic Diseases
Lymphohistiocytosis, Hemophagocytic
Pharyngitis
Respiratory Distress Syndrome, Adult
Splenomegaly
Still's Disease, Adult-Onset