Nucl Med Mol Imaging.  2016 Jun;50(2):123-129. 10.1007/s13139-015-0376-7.

A Comparison Study of Esophageal Findings on 18F-FDG PET/CT and Esophagogastroduodenoscopy

Affiliations
  • 1Department of Nuclear Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemoon-gu, Seoul 120-752, Korea. mdkwj@yuhs.ac

Abstract

PURPOSE
The aim of this study was to compare the esophageal findings of 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography-computed tomography (18F-FDG PET/CT) and esophagogastroduodenoscopy (EGD).
METHODS
We retrospectively reviewed 18F-FDG PET/CT and EGD findings of 369 subjects who underwent medical examination between January 2014 and December 2014. The range and intensity of esophageal 18F-FDG uptake were visually analyzed. The maximum standardized uptake value (SUVmax) of the esophagus and around the esophagogastric (EG) junction was measured. EGD results were provided by the gastroenterologist. We compared the esophageal findings obtained using 18F-FDG PET/CT and EGD.
RESULTS
There were typical linear FDG uptakes in 18F-FDG PET/CT patients who underwent EGD the same day. In visual analysis of the range and intensity of the 18F-FDG uptake, the patients who underwent 18F-FDG PET/CT and EGD on the same day showed relatively diffuse and discernible 18F-FDG uptake in the esophagus. Reflux esophagitis was diagnosed in 59 subjects, and 27 of these were classified as higher than Los Angeles classification A. With an increasing degree of reflux esophagitis observed on EGD, the SUVmax in the esophagus and around the EG junction was also increased.
CONCLUSION
Our study showed that FDG uptake at the esophagus or the EG junction might be clinically significantly related to esophagitis. However, EGD performed before 18F-FDG PET/CT on the same day may affect the esophageal 18F-FDG uptake.

Keyword

Positron emission tomography; Esophagogastroduodenoscopy; Esophagus; Reflux esophagitis; Physiologic activity

MeSH Terms

Classification
Electrons
Endoscopy, Digestive System*
Esophagitis
Esophagitis, Peptic
Esophagus
Fluorodeoxyglucose F18*
Humans
Positron-Emission Tomography
Positron-Emission Tomography and Computed Tomography*
Retrospective Studies
Fluorodeoxyglucose F18
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