Korean J Med.  2007 Dec;73(6):651-655.

A case of hantavirus pulmonary syndrome with hemorrhagic fever with renal syndrome

• Kim MS
• Lee SH
• Park JW
• Do JY
• Yoon KW

Abstract

Hemorrhagic fever with renal syndrome (HFRS) caused by Hantann virus or Seoul virus frequently occurs in Korea. The prodromal clinical symptoms are flu-like symptoms. Rapidly progressive renal failure and hemorrhage follow. Hantavirus pulmonary syndrome (HPS) is usually found in the U.S.A., caused by the Sin-nombre virus. The prodromal symptoms resemble HFRS. However, during the third to fith hospital day after admission, pulmonary edema or pulmonary hemorrhage acutely develops, which results in acute respiratory failure. We here report a case of HFRS with HPS that developed in a 47 year-old man. The patient had flu-like symptoms and diarrhea on admission. Acute renal failure developed and acute hemodialysis was performed. On the fourth hospital day, an asymmetric bilateral haziness as seen on a chest X-ray rapidly developed with reduced O2 saturation, and mechanical ventilation was applied. On the eighth hospital day, the patient was weaned from the ventilator. When acute respiratory failure develops in patients with HFRS, HPS might be considered.

Keyword

Hantavirus pulmonary syndrome; Hemorrhagic fever with renal syndrome

MeSH Terms

Acute Kidney Injury
Diarrhea
Hantavirus Pulmonary Syndrome*
Hantavirus*
Hemorrhage
Hemorrhagic Fever with Renal Syndrome*
Humans
Korea
Middle Aged
Prodromal Symptoms
Pulmonary Edema
Renal Dialysis
Renal Insufficiency
Respiration, Artificial
Respiratory Insufficiency
Seoul virus
Thorax
Ventilators, Mechanical