Korean J Nephrol.  1998 Mar;17(2):348-351.

A Case of HELLP Syndrome Combined with Acute Renal Failure

• Kim SS
• Hwang PJ
• Kim JH
• Bin KT
• Lee KW
• Shin YT

Abstract

The HELLP syndrome(hemolysis, elevated liver enzymes, and low platelets) is a complication of severe preeclampsia or eclampsia and associated with increased maternal and perinatal mortality. Exact pathogenic mechanism is still unclear but the microangiopathic hemolytic anemia combined with endothelial cell damage is suspected to be closely associated with disease process. Variable degree of disseminated intravascular coagulation(DIC) may be accompanied with the HELLP syndrome. We report a case of postpartum HELLP syndrome. She is 24 year-old woman. She showed definite evidence of microangiopathic hemolytic anemia, DIC, elevated liver enzymes and acute renal failure. Liver biopsy revealed fatty change with focal fibrin like material deposition in the portal tract area. She recovered completely with conservative treatment in 2 weeks.

Keyword

HELLP syndrome; Acute renal failure; Postpartum

MeSH Terms

Acute Kidney Injury*
Anemia, Hemolytic
Biopsy
Dacarbazine
Eclampsia
Endothelial Cells
Female
Fibrin
HELLP Syndrome*
Humans
Liver
Perinatal Mortality
Postpartum Period
Pre-Eclampsia
Pregnancy
Young Adult
Dacarbazine
Fibrin