Korean J Nephrol.  2010 Nov;29(6):807-812.

A Case of Acute Fatty Liver of Pregnancy with Renal Subcapsular Hemorrhage

• Ahn CY
• Ryu BK
• Chung JH
• Kim HL

Abstract

Wunderlich syndrome is a spontaneous rupture of the kidney. It is a rare but potentially life-threatening event. The causes are tumor, vascular disease, infection and preeclampsia. Subcapsular hepatic and renal hematoma are rare complications of pregnancy associated with preeclampsia or HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome. Acute fatty liver of pregnancy (AFLP) is rare, but is a fatal complication of the third trimester of pregnancy. The clinical picture consists of liver failure with coagulopathy, encephalopathy and hypoglycemia. Early recognization of the disorder, rapid termination of pregnancy, and intensive supportive care have improved the prognosis. AFLP should be distinguished from HELLP syndrome. AFLP is usually not associated with renal subcapusular hemorrhage. In this report, we describe a 36-year-old nullipara with twin male fetus at 35 weeks of gestation who had developed renal subcapsular hemorrhage in AFLP.

Keyword

Fatty liver; Acute; Pregnancy; Hemorrhage; Kidney

MeSH Terms

Adult
Fatty Liver
Female
Fetus
HELLP Syndrome
Hematoma
Hemorrhage
Humans
Hypoglycemia
Kidney
Liver
Liver Failure
Male
Pre-Eclampsia
Pregnancy
Pregnancy Complications
Pregnancy Trimester, Third
Prognosis
Rupture, Spontaneous
Vascular Diseases
Fatty Liver
Pregnancy Complications