Korean J Nephrol.  2000 Sep;19(5):965-971.

Primary Amyloidosis Presenting Nephrotic Syndrome and Hemorrhagic Gastritis

Affiliations
  • 1Department of Internal Medicine, Kyung-hee university, Seoul, Korea.
  • 2Department of Pathology, Kyung-hee university, Seoul, Korea.

Abstract

A case of a 58 year old woman who was found to have primary amyloidosis is reported. She was presented with nephrotic syndrome and hemorrhgic gastritis. She was confirmed by showing apple green birefringence under the polarized microscope with Congo-red stain through renal and stomach biopsy. Immunoelectrophoresis of urine exhibited Bence-Jones protein(gamma type) and protein electrophoresis of urine exhibited monoclonal gammopathy. She was treated with cyclophosphamide and prednisolone, and proteinuria and gastrointestinal symptoms were improved. We discussed this case with a brief review of literature.

Keyword

Primary amyloidosis(AL); Nephrotic syndrome; Hemorrhagic gastiritis

MeSH Terms

Amyloidosis*
Biopsy
Birefringence
Cyclophosphamide
Electrophoresis
Female
Gastritis*
Humans
Immunoelectrophoresis
Middle Aged
Nephrotic Syndrome*
Paraproteinemias
Prednisolone
Proteinuria
Stomach
Cyclophosphamide
Prednisolone
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