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Mixture of Corni Fructus and Schisandrae Fructus improves testosterone-induced benign prostatic hyperplasia through regulating 5α-reductase 2 and androgen receptor

Hwangbo H, Kim MY, Ji SY, Park BS, Kim T, Yoon S, Kim H, Kim SY, Jung H, Kim T, Lee H, Kim GY, Choi YH

BACKGROUND/OBJECTIVES: Benign prostatic hyperplasia (BPH) characterized by an enlarged prostate gland is common in elderly men. Corni Fructus (CF) and Schisandrae Fructus (SF) are known to have various pharmacological effects,...
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Comprehensive Analysis of the Explanted Systemic Sclerosis Heart: Correlation of Pathologic and Imaging Findings

Lim JH, Lee SY, Na JY, Kim GY, Oh JS, Kim SH

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Development and Internal/External Validation of a Prediction Model for Weight Loss Following Gastric Cancer Surgery: A Multicenter Retrospective Study

Park JH, Kong SH, Park DJ, Yang HK, Kim JW, Park KB, Cho I, Hwang SH, Kim DW, Kim SM, Ryu SW, Gong SC, Jung PY, Ryu H, Kim SG, Choi CI, Kim DH, Choi SI, Park JH, Park DJ, Kim GY, Choi Y, Lee HJ

Purpose: To develop an individualized model for predicting the extent of unintentional weight loss following gastrectomy in patients with gastric cancer based on related risk factors and to externally validate...
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Awake-extracorporeal membrane oxygenation bridged adult heart transplantation: the importance of maintaining isolated cardiac failure

Lim JH, Lee S, Kim SH, Oh JS, Kim GY, Ju MH

Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has been used as a bridge to heart transplantation (HTx). Progression of multi-organ failure during ECMO is a well-known poor prognostic factor for mortality...
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Percutaneous Bone-Anchored Hearing Implant: Is It Clinically Useful in Korean?

Koh SM, Cho YS, Kim GY, Jo M, Seol HY, Moon IJ

Background: The aim of this study is to investigate the clinical effectiveness of Ponto in Korea, a recently released percutaneous bone-anchored hearing implant. Methods: 16 patients with single-sided deafness (SSD) and...
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Development and Roll-Out of A Coronavirus Disease 2019 Clinical Pathway for Standardized Qualified Care in Public Hospitals in Korea

Kwak MY, Jo EY, Chin B, Park SE, Yim J, Lee JE, Jo KE, Kim YS, Lee JE, Yoon YK, Seo YB, Jeong SJ, Kang YM, Joo EJ, Yoon JH, Kim SB, Kim GY, Kim MK

Despite the coronavirus disease 2019 (COVID-19) vaccination roll-out, variant-related outbreaks have occurred repeatedly in Korea. Although public hospitals played a major role in COVID-19 patients’ care, difficulty incorporating evolving COVID-19...
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Induction of apoptotic cell death in human bladder cancer cells by ethanol extract of Zanthoxylum schinifolium leaf, through ROS-dependent inactivation of the PI3K/Akt signaling pathway

Park C, Choi EO, Hwangbo H, Lee H, Jeong JW, Han MH, Moon SK, Yun SJ, Kim WJ, Kim GY, Hwang HJ, Choi YH

BACKGROUND/OBJECTIVES: Zanthoxylum schinifolium is traditionally used as a spice for cooking in East Asian countries. This study was undertaken to evaluate the anti-proliferative potential of ethanol extracts of Z. schinifolium...
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A Case of Heart Transplantation for Fulminant Myocarditis After ChAdOx1 nCoV-19 Vaccination

Kim SH, Lee SY, Kim GY, Oh JS, Kim J, Chun KJ, Ju MH, Lee Ch, Song YJ, Na JY

Vaccines have become the mainstay of management against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease 2019; COVID-19) in the absence of effective antiviral therapy. Various adverse effects...
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Gallic acid-mitochondria targeting sequence-H3R9 induces mitochondria-targeted cytoprotection

Bae Y, Kim GY, Jessa F, Ko KS, Han J

The development of selective targeting of drug molecules towards the mitochondria is an important issue related to therapy efficacy. In this study, we report that gallic acid (GA)-mitochondria targeting sequence...
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Factors Influencing Hearing Aid Adoption in Patients With Hearing Loss in Korea

Cho YS, Kim GY, Choi JH, Baek SS, Seol HY, Lim J, Park JG, Moon IJ

Background: The purpose of this study was two-fold: 1) to identify differences in the characteristics of adopters and non-adopters of hearing aids (HAs); and 2) to investigate factors influencing the...
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Compare Value Congruence of Nurse-Patient Assignment with Work Performance in Neonatal Intensive Care Unit

Kim HM, Kim DY, Kim JY, Kim GY, Moon SH

Purpose: This study aimed to compare the value congruence of nurse-patient assignment (NPA) with work performance in the neonatal intensive care unit (NICU). Methods: Data were collected with 30-items on...
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Heart transplantation in a patient with complex heart lung disease: a case report

Kim SH, Kim GY, Oh JS, Lee SY

Heart disease is often accompanied by lung disease as they share the same risk factors. Heart or lung transplantation is regarded as a definitive treatment for the end-stage disease of...
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Schisandrae Fructus ethanol extract attenuates particulate matter 2.5-induced inflammatory and oxidative responses by blocking the activation of the ROS-dependent NFκB signaling pathway

Lee H, Park C, Kwon DH, Hwangbo H, Kim SY, Kim MY, Ji SY, Kim DH, Jeong JW, Kim GY, Hwang HJ, Choi YH

BACKGROUND/OBJECTIVES: Schisandrae Fructus, the fruit of Schisandra chinensis Baill., has traditionally been used as a medicinal herb for the treatment of various diseases, and has proven its various pharmacological effects,...
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Suppression of Lipopolysaccharide-Induced Inflammatory and Oxidative Response by 5-Aminolevulinic Acid in RAW 264.7 Macrophages and Zebrafish Larvae

Ji SY, Cha HJ, Neelaka Molagoda IM, Kim MY, Kim SY, Hwangbo H, Lee H, Kim GY, Kim DH, Hyun JW, Kim HS, Kim S, Jin CY, Choi YH

In this study, we investigated the inhibitory effect of 5-aminolevulinic acid (ALA), a heme precursor, on inflammatory and oxidative stress activated by lipopolysaccharide (LPS) in RAW 264.7 macrophages by estimating...
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Implementation and Validation of a Gas Chromatography-Mass Spectrometry Method for Pristanic Acid and Phytanic Acid Quantification in Plasma Specimens

Yi A, Lee JH, Yoo G, Lim HJ, Park E, Han J, Kim GY, Cho SE, Lee SG, Lee EH

We validated a gas chromatography-mass spectrometry (GC-MS) method for quantifying pristanic acid (PrA) and phytanic acid (PhA) in plasma specimens. We developed a GC-MS method based on the analysis of 20...
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Clinical Comparison of a Hearing Aid, a Personal Sound Amplification Product, and a Wearable Augmented Reality Device

Seol HY, Kim GY, Kang S, Jo M, Han UG, Cho YS, Hong SH, Moon IJ

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Clinicopathologic features of cutaneous metastases from internal malignancies

Kwon HM, Kim GY, Shin DH, Bae YK

Background: Cutaneous metastasis (CM) is the spread of cancer cells from a primary site to the skin and is rarely the first sign of silent cancer. We investigated the clinicopathological...
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Evaluation of Reduced Port Laparoscopic Distal Gastrectomy Performed by a Novice Surgeon

Park DJ, Lee EJ, Kim GY

Purpose: Reduced port laparoscopic distal gastrectomy (RPLDG) using 3 ports is less invasive than conventional laparoscopic distal gastrectomy (CLDG) using 5 ports. Although RPLDG performed by expert surgeons is safe...
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Experiences With the University Admission Process and Educational Support Among Students With Cochlear Implants in South Korea

Cho YS, Kim GY, Seol HY, Kim EY, Moon IJ

Objectives. The aim of this study was to investigate the current university admission rate and experiences of educational support among students with cochlear implants (CIs) in South Korea. Methods. A prospective...
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A Novel KCNA1 Mutation in an Episodic Ataxia Type 1 Patient with Asterixis and Falls

Lee GB, Kim GY, Jeong IH, Kim N, Kim JW

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