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Emergence of optrA-Mediated Linezolid-Nonsusceptible Enterococcus faecalis in a Tertiary Care Hospital

Park K, Jeong YS, Chang J, Sung H, Kim MN

This study investigated resistance mechanisms and epidemiology of emerging linezolid-nonsusceptible Enterococcus faecalis (LNSEF) in a tertiary care hospital. LNSEF isolated from clinical samples were collected from November 2017 to June...
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Prevalence and Risk Factors for Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae Colonization in Intensive Care Units

Kim YA, Park YS, Kim B, Seo YH, Lee K

Active surveillance culture (ASC) can help detect hidden reservoirs, but the routine use of ASC for extended spectrum β-lactamase-producing Enterobacteriaceae is controversial in an endemic situation. We aimed to determine...
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Proteomic Signatures in Spermatozoa Reveal the Role of Paternal Factors in Recurrent Pregnancy Loss

Mohanty G, Jena SR, Nayak J, Kar S, Samanta L

PURPOSE: To identify the paternal factors responsible for aberrant embryo development leading to loss of foetus in recurrent pregnancy loss (RPL) through proteomic analysis of ejaculated spermatozoa. MATERIALS AND METHODS: This...
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Comparison of Characteristics of Streptococcus dysgalactiae subsp. equisimilis Isolates Causing Repetitive vs Single Infections

Fujita T, Yoshida H, Osaka S, Hirose Y, Goto M, Nagano N, Takahashi

No study has described Streptococcus dysgalactiae subsp. equisimilis (SDSE) isolates that cause repetitive infections (recurrence and reinfection). We compared the microbiological characteristics of SDSE causing repetitive infections with those causing...
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Erythema Elevatum Diutinum with Various Clinicohistological Stages

Cho MY, Kim JH, Kim YC, Kim SC

  • KMID: 2457690
  • Korean J Dermatol.
  • 2019 Aug;57(7):387-390.
A 61-year-old man presented with a 3-year history of erythematous firm nodules on the hands and feet. Histopathological findings of the lesional skin revealed perivascular and diffuse neutrophilic infiltrations on...
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Human spermatozoa anti-proprotein convertase subtilisin/kexin type 4 synthesis using New Zealand rabbit for novel immunocontraception in males

Dahril , Aulanni'am , Keumala V, Mustafa A

PURPOSE: Proprotein convertase subtilisin/kexin type 4 (PCSK4, a 54-kDa protease) is expressed in the plasma membrane of the acrosome in human spermatozoa. It plays a critical role in penetrating the...
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Nosocomial Outbreak Caused by NDM-5 and OXA-181 Carbapenemase Co-producing Escherichia coli

Ahn K, Hwang GY, Kim YK, Kim HY, Jeong HR, Hong JS, Uh Y

Carbapenemase-producing Enterobacteriaceae (CPE) is an important and increasing threat to global health. From July to September 2017, 20 inpatients at a tertiary care hospital in Korea were either colonized or...
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Antimicrobial Susceptibility and Genetic Analysis of Campylobacter jejuni Isolated from Diarrhea Patients in Busan

Park SH, Kim BJ, Kwon YH, Hwang IY, Sung GH, Park EH, Jin SH

BACKGROUND: Campylobacter jejuni is an important food-borne pathogen that causes human gastroenteritis. This study was conducted to investigate the incidence of isolation, antimicrobial susceptibility pattern, and C. jejuni genotype from...
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Accurate and Rapid Measurement of Glycated Hemoglobin Using HLC-723 G11 Variant Mode

Park MS, Lee K, Lee K, Song J, Park HD

BACKGROUND: Type II diabetes mellitus causes many complications, and its prevalence continues to increase in Korea. Accurate measurement of glycated Hb (HbA1c) is important because of its usefulness in diagnosis,...
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The effect of cigarette smoking on Porphyromonas gingivalis, a crucial periodontal pathogen

Shin J, Lee SW

Smoking is implicated as one of the most significant risk factors for periodontal disease. The objective of this study was to examine the effect of cigarette smoke extract (CSE), on...
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The degree of major histocompatibility complex matching between purebred Maltese and mongrel dogs using microsatellite markers

Kwak HH, Woo HM, Park KM

Long-term maintenance of transplanted organs is one of the major factors that increases survival time of recipients. Although obtaining a major histocompatibility complex (MHC)-matched donor with the recipient is essential...
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Microcytosis in children and adolescents with the sickle cell trait in Basra, Iraq

Jaber RZ, Hassan MK, Al-Salait

BACKGROUND: Microcytic anemia, the most common form of anemia in children and adolescents, is a heterogeneous group of diseases that is acquired or inherited. We assessed the frequency and causes...
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Recent progress in laboratory diagnosis of thalassemia and hemoglobinopathy: a study by the Korean Red Blood Cell Disorder Working Party of the Korean Society of Hematology

Lee YK, Kim HJ, Lee K, Park SH, Song SH, Seong MW, Kim M, Han JY

Genetic hemoglobin disorders are caused by mutations and/or deletions in the α-globin or β-globin genes. Thalassemia is caused by quantitative defects and hemoglobinopathies by structural defect of hemoglobin. The incidence...
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Campylobacter jejuni Foodborne Infection Associated with Cross-contamination: Outbreak in Seoul in 2017

Kang CR, Bang JH, Cho SI

BACKGROUND: In July 2017, there was an outbreak of Campylobacter jejuni infection in three auxiliary police squads in Seoul, Korea. An epidemiological investigation was conducted to identify the cause and...
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Identification and Characterization of NDM-1-producing Hypervirulent (Hypermucoviscous) Klebsiella pneumoniae in China

Liu Z, Gu Y, Li X, Liu Y, Ye Y, Guan S, Li J

BACKGROUND: Carbapenem-resistant hypervirulent (hypermucoviscous) Klebsiella pneumoniae (CR-HMKP) poses a significant public health challenge. We investigated its epidemiology and molecular characteristics in a tertiary care hospital in eastern China. METHODS: CR-HMKP were...
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Increased Prevalence of Thalassemia in Young People in Korea: Impact of Increasing Immigration

Lee HJ, Shin KH, Kim HH, Yang EJ, Park KH, Kim MJ, Kwon JR, Choi YS, Kim JN, Shin MG, Cho YG, Kim SJ, Kim KH, Jeong S, Kong SG, Jung YJ, Lee N, Kim MJ, Seong MW

BACKGROUND: Thalassemia is highly prevalent in Southeast Asia but is rare in Korea; however, Southeast Asian immigrant population is recently rising in Korea. We investigated the prevalence of thalassemia in...
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Specification of Bacteriophage Isolated Against Clinical Methicillin-Resistant Staphylococcus Aureus

Nasser A, Azizian R, Tabasi M, Khezerloo , Heravi FS, Kalani MT, Sadeghifard N, Amini R, Pakzad I, Radmanesh , Jalilian F

OBJECTIVES: The emergence of resistant bacteria is being increasingly reported around the world, potentially threatening millions of lives. Amongst resistant bacteria, methicillin-resistant Staphylococcus aureus (MRSA) is the most challenging to...
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Capsaicin-Induced Apoptosis in MBT-2 Murine Bladder Tumor Cells and Bladder Wall Penetration Effect of the Nano-Encapsulated Capsaicin in Rabbit

Cho SJ, Moon HW, Bae WJ, Park YH, Ha US, Hong SH, Kim SW, Lee JY

PURPOSE: In this study, we attempted to characterize capsaicin's effects with regard to the apoptosis of murine bladder cancer cells (MBT-2) as well as the pharmacodynamics of nano-encapsulated capsaicin formulation...
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Identification of proteins differentially expressed by glutamate treatment in cerebral cortex of neonatal rats

Kang JB, Park DJ, Koh PO

Glutamate leads to neuronal cell damage by generating neurotoxicity during brain development. The objective of this study is to identify proteins that differently expressed by glutamate treatment in neonatal cerebral...
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LGR5 and Downstream Intracellular Signaling Proteins Play Critical Roles in the Cell Proliferation of Neuroblastoma, Meningioma and Pituitary Adenoma

Hwang M, Han MH, Park HH, Choi H, Lee KY, Lee YJ, Kim JM, Cheong JH, Ryu JI, Min KW, Oh YH, Ko Y, Koh SH

Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) has been reported to play critical roles in the proliferation of various cancer cells. However, the roles of LGR5 in brain tumors and...
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