Korean J Nephrol.
2004 Jul;23(4):644-648.
A Case of Bilateral Oncocytomatosis in Chronic Renal Failure
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Inje University, Korea. hansy@medimail.co.kr
- 2Department of Radiology, College of Medicine, Inje University, Korea.
- 3Department of Pathology, College of Medicine, Inje University, Korea.
- 4Department of Pathology, College of Medicine, Ulsan University, Korea.
Abstract
- Renal oncocytoma is a uncommon benign tumor originating from the intercalated cells of the collecting duct, which occurs with an overall incidence of 3% to 7% among all renal tumors. Bilateral, multicentric renal oncocytoma is rare, especially in chronic renal failure. We report a case of 59-year-old woman with bilateral oncocytoma with renal failure. She presented nausea and vomiting for one month, and had no previous past medical history. Abdominal sonography and computed tomography revealed variable sized homogenous mass on both kidneys. Microscopic examination showed large polygonal cells with abundant eosinophilic and granular cytoplasm. Surrounding renal parenchyma revealed marked atrophy and sclerosis with a few intact glomeruli and tubules. We could exclude renal cell carcinoma because tumor cells were negative for CK7, CK20, vimentin, and Hale's colloidal iron staining, and did not show perinuclear halo and mitosis.
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