Korean J Blood Transfus.  1997 May;8(1):49-57.

Evaluation of Platelet Concentrates Stored in the Second Generation Platelet Storage Containers

• Jeon DS
• Choi GJ
• Jang YW
• Chun HJ
• Kim JR
• Song DH

Abstract

BACKGROUND
Platelets can be stored for 3days at 22degrees C in conventional plastic bags plasticizer with di-(2-ethylhexyl)phthalate(DEHP). However, with such a short interval for storage, platelets could not be made easily available for thrombocytopenic patients. In vitro platelet function during 5 days of storage at 22degrees C was studied in a new plastic bag (second generation bag) which contained as plasticizer a tri (2-ethylhexyl)trimellitate and developed in Korea (Boin Medica Co.).
METHODS
In vitro function (mean platelet volume, platelet distribution width, pH, platelet aggregation, platelet morphology and swirling phenomenon) was evaluated in 20 units of platelet concentrate at day 0, 2, 5 while mixing in 60 rpm platelet rotator at 22degrees C.
RESULTS
At day 5, platelet count, mean platelet volume, platelet distribution width, pH, platelet aggregation, platelet morphology and swirling phenomenon were well maintained. pO2, pCO2 and HCO3- were 65.6mmHg, 43.4mmHg and 12.3mmol/L at day 5, respectively.
CONCLUSION
The data indicate that the use of the new platelet storage container will permit satisfactory storage for at least 5 days at 22degrees C.

Keyword

Second generation platelet storage container Tri(2-ethylhexyl)trimellitate

MeSH Terms

Blood Platelets*
Humans
Hydrogen-Ion Concentration
Korea
Mean Platelet Volume
Plastics
Platelet Aggregation
Platelet Count
Plastics