Korean J Blood Transfus.  1998 Dec;9(2):253-258.

Evaluation of a domestic second generation platelet storage container

Affiliations
  • 1Department of Clinical Pathology, Seoul National University College of Medicine, Seoul, Korea.
  • 2Department of Clinical Pathology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

BACKGROUND
Polyvinyl (PVC) plastic container plasticized with di-(2-ethylhexyl) phthalate (DEHP) has been used for the storage of platelet concentrates for five days in Korea. Authors evaluated a second generation platelet storage container plasticized with tri (2-ethylhexyl) phthalate (TOTM) which was recently produced by Green Cross Medical Corp.(Korea).
METHODS
30 units of platelet concentrates were stored in TOTM-PVC container at 22'C in a flatbed agitator. Samples were taken at day 1,3,5, and 7 from the containers and tested for platelet count, MPV, PDW, pH, HCO3-,LDH, lactate, hypotonic shock response and beta-thromboglobulin (beta-TG). Electron microscopic examination was also performed.
RESULTS
The number and functions of platelets were well preserved during storage. pH was maintained above 6.8 and any evidence for platelet activation was minimal.
CONCLUSION
The TOTM-PVC second generation platelet storage container recently produced by the Green Cross Medical Corp.(Korea) was able to preserve platelets for at least five days without significant storage lesions.

Keyword

PVC-TOTM; Tri(2-ethylhexyl) phthalate; Second generation platelet storage container

MeSH Terms

beta-Thromboglobulin
Blood Platelets*
Dihydroergotamine
Hydrogen-Ion Concentration
Korea
Lactic Acid
Osmotic Pressure
Plastics
Platelet Activation
Platelet Count
Polyvinyls
Dihydroergotamine
Lactic Acid
Plastics
Polyvinyls
beta-Thromboglobulin
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