Korean J Nephrol.
2008 Jul;27(4):518-523.
A Case of Adult-onset Henoch-Schonlein Purpura (HSP) Combined with Post-infectious Glomerulonephritis (PIGN)
- Affiliations
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- 1Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea. visionjcys@eulji.ac.kr
- 2Department of Pediatrics, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea.
- 3Department of Pathology, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea.
- 4Department of Radiology, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea.
Abstract
- Henoch-Schonlein purpura (HSP) is a small-vessel vasculitis that are predominantly observed in children, affecting their skin, joints, gut and kidneys. The renal prognosis of HS nephritis is known to be worse in adults than in children. It is defined by tissue deposition of IgA. In most HSP patients, serum complement levels are usually normal. However, some authors reported abnormalities of serum complement levels in children-onset HSP. The authors report here a rare adult-onset case of HSP combined with post-infectious glomerulonephritis, especially hypocomplementemia and subepithelial 'hump'- like electron dense deposits.
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