Korean J Hematol.  2007 Dec;42(4):419-422. 10.5045/kjh.2007.42.4.419.

Small Intestinal Mucosa Associated Lymphoid Tissue (MALT) Lymphoma in a Child Presenting with Recurrent Intussusception: A Case Report

• Seo HE
• Lee JH
• Park TI
• Lee KS

• KMID: 2252230
• DOI: http://doi.org/10.5045/kjh.2007.42.4.419

Abstract

Mucosa associated lymphoid tissue (MALT) lymphoma is a malignant B cell lymphoma that develops from MALT. The stomach is the most common site of MALT lymphomas but be found anywhere in the body. Adult MALT lymphomas are not rare diseases, but in children, intestinal MALT lymphomas are very rare. We treated a 12-year-old boy who underwent segmental resection of the small intestine due to recurrent intussusceptions, 2 months apart, and was diagnosed with an intestinal MALT lymphoma. He received multiple chemotherapeutic agents (vincristin, cyclophosphamide, prednisone, methotrexate, doxorubicin and cytosine arabinoside) according to the CCG-5961 protocol for 3 months. Currently, he is alive and disease free.

Keyword

Intestinal mucosa associated lymphoid tissue lymphoma; Recurrent intussusception; Chemotherapy

MeSH Terms

Adult
Child*
Cyclophosphamide
Cytosine
Doxorubicin
Drug Therapy
Humans
Intestinal Mucosa*
Intestine, Small
Intussusception*
Lymphoid Tissue*
Lymphoma*
Lymphoma, B-Cell
Lymphoma, B-Cell, Marginal Zone
Male
Methotrexate
Mucous Membrane
Prednisone
Rare Diseases
Stomach
Cyclophosphamide
Cytosine
Doxorubicin
Methotrexate
Prednisone

Figure

• 

  Fig. 1 Contrast enhanced CT scan demonstrates ileo-ileal type of intussusception (A) and polyp (B) in the right lower abdominal cavity.

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  Fig. 2 Microscopic finding of intestinal MALT lymphoma. (A) Reactive lymphoid follicles and intermediate lymphocytes in lamina propria and submucosal area (H&E stain, ×100). (B) Diffuse infiltration of small to medium sized atypical lymphoid cells with irregular nuclear membrane and clump chromatin pattern and plasma cell infiltration (H&E stain, ×400).

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