Korean J Med.  1998 Jul;55(1):127-130.

A Case of Systemic Lupus Erythematosus Associated With Myelofibrosis

Affiliations
  • 1Department of Internal Medicine, Han Dong University, Sulin Prebyterian Hospital, Pohang, Korea.

Abstract

Myelofibrosis is characterized by excessive deposition of collagen, laminin and fibronectin within the bone marrow stroma. These change can be due to primary myeloproliferative disorders, a variety of malignant process, endocrine disturbances, or inflammatory disease. Clinical and laboratory finding are suggest in the immune process with myelofibrosis. It has been rarely reported that myelofibrosis coexisting with SLE. This is a case report of systemic lupus erythematosus coexisting with bone marrow fibrosis in a 44 years old female patient presenting with menorrhagia, syncope and palpitation. We report the case with relevant literature review. Treatment with corticosteroid in a patient with SLE and myelofibrosis remit to the clinical and hematologic abnormalities.

Keyword

Systemic lubpus erythematosus Myelofibrosis

MeSH Terms

Adult
Bone Marrow
Collagen
Female
Fibronectins
Humans
Laminin
Lupus Erythematosus, Systemic*
Menorrhagia
Myeloproliferative Disorders
Primary Myelofibrosis*
Syncope
Collagen
Fibronectins
Laminin
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