Korean J Dermatol.
2006 Aug;44(8):995-997.
A Case of Generalized Granuloma Annulare Controlled by Isotretinoin
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- 1Department of Dermatology, College of Medicine, Soonchunhyang University, Seoul, Korea. topdoctor@naver.com
Abstract
- Generalized granuloma annulare (GGA) is an uncommon type of granuloma annulare. It is frequently characterized by chronicity and unresponsiveness to a number of therapeutic modalities. A variety of systemic treatment modalities for GGA have been tried, including PUVA, dapsone, hydroxychloroquine, systemic corticosteroids, niacinamide, vitamin E and chlorambucil. However, their efficacy was not very encouraging. We present a case of GGA which showed a satisfactory response to isotretinoin. To conclude, isotretinoin may be considered as treatment for GGA in patients with unacceptable cosmetic disfigurements or symptoms.
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