Clinico-pathologic study of the 40 cases endometrial carcinoma

Lee, K S; Lee, H B; Kang, J B; Kim, H B; Lee, K Y; Lee, Y W; Park, Y S; Kang, S W

Abstract

BACKGROUND: This study evaluated the characteristics of clinical and pathological profile at diagnostic cases of the endometrial cancer in the Hallym University Hospital. The purpose was to determine prognostic factors and differences of endometrial carcinoma in our country.
METHODS
This retrospective study was based on chart review. This study enrolled 40 patients with endometrial carcinoma from 1984 to 1994 who are managed in department of Obstetrics and Gynecology at Hallym University Hospital. We focused on the age, symptoms, risk factors, surgical stage, histologic features and univariate analysis of prognostic factors for 5 year survival rate.
RESULTS
The mean age at diagnosis was 51.1 years old and main symptom is vaginal bleeding 87.5%, and postmenopausal women are 67.5%. The principal diagnostic tool is endometrial biopsy, and the other noninvasive screening test is remained to develop. The pathologic subtypes were adenocarcinoma 80%, adenosquamous carcinoma 17.5%, papillary serous carcinoma 2.5% and the surgical stage were stage I 60%, stage II 7.5%, stage III 12.5%, stage IV 10%. The 5 years survival rate by stage & pathologic findings were stage I 79%, II 33%, III 20%, IV 0%, adenocarcinoma 78%, adenosquamous carcinoma 57%.
CONCLUSION
We know that clinical features of endometrial carcinoma in our country is similar to western country, but infertility was not risk factor in our study and the age at diagnosis is younger and advanced disease is more and the prognosis in the advanced disease is poor than western country.