Korean J Hepatobiliary Pancreat Surg.  2002 Jun;6(1):111-115.

Acinar Cell Carcinoma of the Pancreas: A case report

Affiliations
  • 1Department of Surgery, Holy Family Hospital, College of Medicine, the Catholic University of Korea, Korea. kimwook@hfh.cuk.ac.kr

Abstract

Acinar cell carcinoma of the pancreas is an uncommon neoplasm, comprises about 1% of pancreatic non-endocrine malignancies, arising from the pancreatic exocrine acinar cells rather than from ductal or neuroendocrine cells. Only ten cases of pancreatic acinar cell carcinoma has been reported in Korea. We reported a case of pancreatic acinar cell carcinoma in 50-year-old female with an one month history of rapid growing mass on epigastrium. Computed tomography shows a huge mass measured 12x11 cm, appeared cystic, in the body and tail of the pancreas. The patient underwent a distal pancreatectomy with splenectomy and total gastrectomy because of severe adhesion to the posterior gastric wall. After operation, the patient went rather rapidly downhill with progressive enlargement of peripancreatic lymph nodes, progression of pre-existing portal vein thrombosis and liver, bone metastasis inspite of adjuvant chemoradiotherpy and finally expired 17 months after operation.

Keyword

Acinar cell carcinoma; Pancreas

MeSH Terms

Acinar Cells*
Carcinoma, Acinar Cell*
Female
Gastrectomy
Humans
Korea
Liver
Lymph Nodes
Middle Aged
Neoplasm Metastasis
Neuroendocrine Cells
Pancreas*
Pancreatectomy
Splenectomy
Venous Thrombosis
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