Korean J Med.  2009 Apr;76(4):506-509.

A case of acinar cell carcinoma of the pancreas

Affiliations
  • 1Department of Internal Medicine, Daegu Fatima Hospital, Daegu, Korea. stemcell@hanafos.com
  • 2Department of Surgery, Daegu Fatima Hospital, Daegu, Korea.
  • 3Department of Pathology, Daegu Fatima Hospital, Daegu, Korea.

Abstract

Acinar cell carcinoma of the pancreas is a rare tumor that constitutes 1~2% of all pancreatic cancers. The clinical and radiologic findings are inconclusive when diagnosing this disease. Acinar cell carcinoma progresses rapidly and metastasizes early, resulting in a poor prognosis. A 41-year-old man was admitted for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography (PET)-CT showed a splenic mass involving the pancreatic tail with increased 18F-fluorodeoxyglucose (18F-FDG) uptake. A primary radical distal pancreatectomy and splenectomy were carried out. The pathology revealed acinar cell carcinoma of the pancreas. Three months later, a gastric recurrence was detected and a total gastrectomy was performed. Four months later, multiple hepatic metastases were found and a left hepatectomy was carried out. During treatment with capecitabine, no evidence of tumor progression was observed for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma that did not progress for 14 months with capecitabine treatment.

Keyword

Pancreas; Carcinoma; Acinar cell; Capecitabine

MeSH Terms

Abdominal Pain
Acinar Cells
Adult
Carcinoma, Acinar Cell
Deoxycytidine
Fluorouracil
Gastrectomy
Hepatectomy
Humans
Neoplasm Metastasis
Pancreas
Pancreatectomy
Pancreatic Neoplasms
Positron-Emission Tomography
Prognosis
Recurrence
Splenectomy
Capecitabine
Deoxycytidine
Fluorouracil
Full Text Links
  • KJM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr