Korean J Hepatol.
2001 Jun;7(2):201-205.
Combined Hepatocellular and Cholangiocarcinoma, Separate Type: A Case Report
- Affiliations
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- 1Department of Pathology, Chonbuk National University Medical School, Jeonju, Korea.
- 2Department of Radiology, Chonbuk National University Medical School, Jeonju, Korea. mws@moac.chonbuk.ac.kr
- 3Department of Surgery, Chonbuk National University Medical School, Jeonju, Korea.
- 4Institute for medical science, Chonbuk National University Medical School, Jeonju, Korea.
Abstract
- Combined hepatocellular and cholangiocarcinoma (cHCC-CC) is an uncommon form of primary liver cancer having features of both hepatocellular and billiary epithelial differentiation. We reptitis B virus. A 36-year-old woman was diagnosed by ultrasonography with an asymptomatic tumor inort a case of cHCC-CC that separately developed in a patient who was serologically positive for hepa the left lobe of the liver. Based on radiologic and serologic findings of elevated serum alpha-fetoprotein (AFP) level, a preoperative diagnosis of hepatocellular carcinoma was made. A left lobectomy of the liver was done. On histological examination, the resected tumor was shown to consist of two separated masses. One was hepatocellular carcinoma that showed immunoreactivity for AFP. The other was cholangio- carcinoma that showed immunoreactivity for cytokeratin-19 (CK-19) in a separate form.
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