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Changing incidence and survival of intrahepatic cholangiocarcinoma based on Surveillance, Epidemiology, and End Results Database (2000–2017)

Ali H, Tedder B, Waqar SH, Mohamed R, Cate EL, Ali E

Backgrounds/Aims: Historically, the incidence and prognosis of patients diagnosed with intrahepatic cholangiocarcinoma (ICC) have been inadequately understood. Survival analysis in ICC has yet to be investigated in a population-based study. Methods:...
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Incidence, mortality, and survival of liver cancer using Korea central cancer registry database: 1999–2019

Hong SY, Kang MJ, Kim T, Jung KW, Kim BW

Backgrounds/Aims: Historically, incidence and survival analysis and annual traits for primary liver cancer (LC) has not been investigated in a population-based study in Korea. The purpose of the current study...
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Relationship between Clonorchis sinensis Infection and Cholangiocarcinoma in Korea

Kim HS, Nam HW, Ahn HJ, Kim D, Kim YH

This study provides an overview of the current status of clonorchiasis and cholangiocarcinoma (CCA), and their relationship in Korea during 2012-2020. Data were obtained from the Health Insurance Review &...
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Neoadjuvant and Adjuvant Chemotherapy for Cholangiocarcinoma

Lee HS

Cholangiocarcinoma consists of a heterogeneous group of aggressive and rare malignancies that arise from the bile ducts outside or inside the liver. Although surgical resection remains the only potential curative...
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Portal Biliopathy Misdiagnosed as Hilar Cholangiocarcinoma

Kim SY, Moon SH, Cho YA, Lee SM, Kim JH

Portal biliopathy refers to the changes in the bile duct caused by portal vein thrombosis or obstruction. It is assumed to be caused by cavernous transformation due to the development...
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Intrahepatic cholangiocarcinoma: Tumour heterogeneity and its clinical relevance

Komuta M

Treatment of intrahepatic cholangiocarcinoma (iCCA) is currently at a significant turning point due to the identification of isocitrate dehydrogenase (IDH) mutations and fibroblast growth factor receptor (FGFR) fusions that can...
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Genetic, Clinicopathological, and Radiological Features of Intrahepatic Cholangiocarcinoma with Ductal Plate Malformation Pattern

Chung T, Rhee H, Shim HS, Yoo JE, Choi GH, Kim H, Park YN

Background/Aims: Intrahepatic cholangiocarcinoma (iCCA) with a ductal plate malformation (DPM) pattern is a recently recognized rare variant. The genomic profile of iCCA with DPM pattern needs to be elucidated. Methods: Cases...
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Intraductal Radiofrequency Ablation as a Palliative Treatment for Advanced Malignant Hilar Biliary Obstruction

Kang H, Kim EJ, Kim YS

Malignant hilar biliary obstruction (MHBO) frequently accompanies cholestasis and cholangitis, and requires biliary stent placement. To prevent stent occlusion and prolong survival, local ablation therapy can be considered adjunctive...
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The prognostic value of the lymph node ratio in patients with distal cholangiocarcinoma after curative intended surgery: A single-center retrospective study

Oh C, Kim HJ, Song SH, Park EK, Hur YH, Koh YS, Cho CK

Backgrounds/Aims: The goal of the present study was to evaluate the prognostic value of lymph node ratio (LNR) in distal cholangiocarcinoma (DCC) after curative intended surgery. Methods: Clinicopathological data of 162...
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Comparing palliative treatment options for cholangiocarcinoma: photodynamic therapy vs. radiofrequency ablation

Mohammad T, Kahaleh M

Referral to an endoscopist is often done once curative resection is no longer an option for cholangiocarcinoma management. In such cases, palliation has become the main objective of the treatment....
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Novel Palliative Chemotherapy for Cholangiocarcinoma

Jung JW, Woo SM

The term cholangiocarcinoma (CC) refers to all tumors arising from bile duct epithelium. CCs are characterized by their rarity, difficulty in diagnosis, and overall poor prognosis. This leads to a...
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Confocal Laser Endomicroscopy in the Diagnosis of Biliary and Pancreatic Disorders: A Systematic Analysis

Kim DH, Krishna SG, Coronel E, Kröner PT, Wolfsen HC, Wallace MB, Corral JE

Background/Aims: Endoscopic visualization of the microscopic anatomy can facilitate the real-time diagnosis of pancreatobiliary disorders and provide guidance for its treatment. This study aimed to review the technique, image classification,...
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Comparison of oncologic outcomes of extrahepatic cholangiocarcinoma according to tumor location: perihilar cholangiocarcinoma versus distal bile duct cancer

Lee JM, Kim H, Sohn HJ, Choi YJ, Kang JS, Han Y, Kwon W, Jang JY

Purpose: Extrahepatic cholangiocarcinoma is distinguished into perihilar cholangiocarcinoma (PHC) and distal bile duct cancer (DBC). The studies for each subtype have been conducted separately. This study compared oncological outcomes between...
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Diagnosis and Management of Biliary Tract Cancer

Yoon JH

Biliary tract cancer (BTC) are highly aggressive and fatal malignancies. As one of the leading cause of death in Republic of Korea, BTC amoung various malignancies has been one of...
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Inflammatory Myofibroblastic Tumor Misdiagnosed as Intrahepatic Cholangiocarcinoma

Park JW, Han SH, Kim DK

An inflammatory myofibroblastic tumor (IMT) is a rare tumor that is currently classified as an intermediate cancer according to the World Health Organization classification system. The pathophysiology of its occurrence...
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Diagnostic Image Feature and Performance of CT and Gadoxetic Acid Disodium-Enhanced MRI in Distinction of Combined HepatocellularCholangiocarcinoma from Hepatocellular Carcinoma

Kim H, Kim Ss, Lee S, Lee M, Kim MJ

Purpose: To find diagnostic image features, to compare diagnostic performance of multiphase CT versus gadoxetic acid disodium-enhanced MRI (GAD-MRI), and to evaluate the impact of analyzing Liver Imaging Reporting and...
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Patch venoplasty for resecting tumor invading the retrohepatic inferior vena cava using total and selective hepatic vascular exclusion

Kim SM, Hwang S, Moon DB, Jung DH, Lee SG

Large hepatic tumors can invade the retrohepatic inferior vena cava (IVC). Resecting the involved IVC wall is necessary to achieve complete tumor resection. We present detailed surgical procedures of IVC...
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Bile Acid Receptors in Cholangiocyte

Park JM

Bile acids are known to play a role in helping the digestion of lipid and maintenance of the bile flow. However, since the first bile acid receptor was discovered in...
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68Ga-FAPI-46 PET/MR Detects Recurrent Cholangiocarcinoma and Intraductal Papillary Mucinous Neoplasm in a Patient Showing Increasing CEA with Negative 18F-FDG PET/CT and Conventional CT

Siripongsatian D, Promteangtrong C, Kunawudhi A, Kiatkittikul P, Chotipanich C

A patient with intrahepatic cholangiocarcinoma who underwent hepatic resection with completed neoadjuvant chemotherapy presented with increased CEA levels. Previous whole abdominal and chest CT scan revealed no evidence of local...
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Portal vein arterialization following a radical left extended hepatectomy for Klatskin tumor: A case report

Basso CD, Meniconi RL, Usai S, Guglielmo N, Colasanti M, Ferretti S, Sandri GBL, Ettorre GM

Portal vein arterialization (PVA) has been attracting attention for its role as a salvage inf low technique in various clinical applications. Initially performed in shunt surgery for portal hypertension, with the...
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