Korean J Anesthesiol.  1991 Jun;24(3):690-692. 10.4097/kjae.1991.24.3.690.

Anesthesia for Open Heart Surgery in Patient with Cold Agglutinin

Affiliations
  • 1Department of Anesthesiology, Catholic University Medical College, Seoul, Korea.

Abstract

Cold agglutinins are serum antibodies activated at low temperature to produce red blood cell agglutination and hemolysis. Hypothermic cardiopulmonary bypass has potential danger to patient with positive cold agglutinin titer. We report a successful anesthesia for mitral valve replacement surgery in a patient who has high cold agglutinin titer. To avoid problem, the cold agglutinin titer was reduced by plasmapheresis and hypothermia was maintained above the critical temperature. There was no severe complication except mild hemoglobinuria.

Keyword

Cold agglutinin; Cardiopulmonary bypass; Hypothermia

MeSH Terms

Agglutination
Agglutinins
Anesthesia*
Antibodies
Cardiopulmonary Bypass
Erythrocytes
Heart*
Hemoglobinuria
Hemolysis
Humans
Hypothermia
Mitral Valve
Plasmapheresis
Thoracic Surgery*
Agglutinins
Antibodies
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