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ABO-incompatible liver transplantation using only rituximab for patients with low anti-ABO antibody titer

Lee B, Choi Y, Han HS, Yoon YS, Cho JY, Jeong SH, Kim JW, Jang ES, Ahn S

BACKGROUNDS/AIMS: Graft survival after ABO-incompatible (ABOi) living donor liver transplantation (LDLT) has increased due to advances in desensitization methods. We analyzed early outcomes following ABOi LDLT using only rituximab without...
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A Pediatric Case of a D-Penicillamine Induced ANCA-associated Vasculitis Manifesting a Pulmonary-Renal Syndrome

Kang S, Cho MH, Hyun H, Kim JH, Ko JS, Kang HG, Cheong HI, Kim WS, Moon KC, Ha IS

D-penicillamine has been reported to cause antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis presenting as rapidly progressive glomerulonephritis or pulmonary-renal syndrome mostly in adults. We report a pediatric case of D-penicillamine induced...
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Desensitization in HLA Incompatible Transplantation

Park BG

In terminally ill patients, organ transplantation could be recommended as the treatment of choice. In Korea, living donor liver or kidney transplantation is much more frequent than deceased donor transplantation...
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Recent Concepts of Guillain-Barré Syndrome

Yoon BA, Bae JS, Kim JK

Guillain-Barré syndrome (GBS) is a representative form of post-infectious autoimmune neuropathy with heterogenous manifestations. It was originally considered as an ascending demyelinating polyneuropathy in Western countries. However, the discovery of...
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Differential Diagnosis and Treatment of Thrombotic Microangiopathy Syndrome

Hong J

Diagnosis of thrombotic microangiopathy (TMA) is challenging due to its close association with other forms of microangiopathic hemolytic anemia, such as malignant hypertension and disseminated intravascular coagulation, and because other...
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Successful treatment of early acute antibody-mediated rejection in an human leukocyte antigen-incompatible and ABO-incompatible living-donor kidney transplant patient

Gang S, Han A, Min SI, Ha J, Yang J

For successful human leukocyte antigen-incompatible (HLAi) or ABO-incompatible (ABOi) living-donor kidney transplantations (LDKTs), pretransplant desensitization is essential; however, early antibody-mediated rejection (ABMR) remains the most important complication after HLAi or...
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Catastrophic Antiphospholipid Syndrome Associated with Systemic Lupus Erythematosus Successfully Treated with Rituximab: A Case Report

Shin J, Kim KN

The catastrophic variant of antiphospholipid syndrome (APS) is a very rare and life-threatening condition of APS. This condition is characterized by thrombosis in multiple organs within a short period of...
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Bortezomib Treatment for Refractory Antibody-Mediated Rejection Superimposed with BK Virus-Associated Nephropathy during the Progression of Recurrent C3 Glomerulonephritis

Do W, Lee JH, Kim KJ, Han MH, Jung HY, Choi JY, Park SH, Kim YL, Kim CD, Cho JH, Yang Y, Kim M, Hwang I, Kim KY, Yim T, Kim YJ

A 38-year-old man, who underwent a second kidney transplantation (KT), was admitted because of antibody-mediated rejection (AMR) complicated by BK virus-associated nephropathy (BKVAN). He was placed on hemodialysis at the...
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Double filtration plasmapheresis in the treatment of hyperproteinemia in dogs affected by Leishmania infantum

Perondi F, Brovida C, Ceccherini G, Guidi G, Lippi I

Three dogs were evaluated for severe hyperproteinemia and hyperglobulinemia secondary to Leishmania infantum. Double filtration plasmapheresis (DFPP) was performed in two dogs at days 1, 2, and 6 after presentation....
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Atypical hemolytic uremic syndrome and eculizumab therapy in children

Kim SH, Kim HY, Kim SY

Hemolytic uremic syndrome (HUS) is often encountered in children with acute kidney injury. Besides the well-known shiga toxin-producing Escherichia coli-associated HUS, atypical HUS (aHUS) caused by genetic complement dysregulation has...
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The Current Global Status and Production Trends of Plasma Fractionation

Kim MJ, Burnouf T

The demand for medicinal products derived from plasmas are increasing on a global scale. In particular, the demand for intravenous immunoglobulin has continuously been increasing. The increase in the capacity...
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Ceftizoxime-induced immune hemolytic anemia associated with multi-organ failure

Huh JY, Ahn A, Kim H, Kwon SW, An S, Lee JY, Kwon BS, Oh EH, Park DH, Huh JW

Drug-induced immune hemolytic anemia (DIIHA) is a rare side effect of drugs. DIIHA may cause a systemic inflammatory response that results in acute multi-organ failure and death. Ceftizoxime belongs to...
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Acute Combined Central and Peripheral Demyelination in Children: in Comparison with Isolated Demyelinating Disease

Byun JH, Song JY, Kong J, Nam SO, Kim YM, Yeon GM, Lee YJ

PURPOSE: This study aimed to describe the clinical characteristics and outcomes of children with acute combined central and peripheral nervous system demyelination (CCPD); and compare with the children of isolated...
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Clinical analysis of single filtration plasmapheresis using continuous renal replacement therapy machines in kidney transplantation

Lim E, Kim Y, Jeong JC, Park I, Kim H, Lee SH, Oh CK, Shin GT

BACKGROUND: Plasmapheresis has become an essential element of kidney transplantation (KT). In the present study, we report clinical outcomes of filtration plasmapheresis using continuous renal replacement therapy machines with a...
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A 1-month-old infant with chylomicronemia due to GPIHBP1 gene mutation treated by plasmapheresis

Jung MK, Jin J, Kim HO, Kwon A, Chae HW, Kang SJ, Kim DH, Kim HS

Chylomicronemia is a severe type of hypertriglyceridemia characterized by chylomicron accumulation that arises from a genetic defect in intravascular lipolysis. It requires urgent and proper management, because serious cases can...
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Anti-N-methyl-D-aspartate Receptor (NMDAR) Encephalitis: Neuronal Burden of a Comorbid Ovarian Teratoma

Hwang J, Byeon JH, Kim GH, Eun SH, Eun BL

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a disease that is characterized by acute psychiatric symptoms, seizures, and central hypoventilation. Patients with anti-NMDAR encephalitis exhibit speech alterations, insomnia, seizures, and movement disorders....
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Fatal Invasive Pulmonary Aspergillosis after Combined Induction with Rituximab and Antithymocyte Globulin for Kidney Transplantation in a Sensitized Recipient, and Early Rejection Therapy with Plasmapheresis and Low-dose Immunoglobulin

Jeong DW, Lee SH, Moon JY, Kim YG, Lee YH, Kim K, Park H, Joo SH

A high degree of sensitization to human leukocyte antigen requires more intensive induction therapy; however, this increases vulnerability to opportunistic infections following kidney transplantation. Although recent studies have suggested that...
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A Case of Thrombotic Thrombocytopenic Purpura with Exacerbation after Incomplete Remission of Therapeutic Plasma Exchange

Sohn YH, Ihm C, Choi EH, Lee SK

Thrombotic thrombocytopenic purpura (TTP) is a rare blood disorder with a mortality rate of over 90% without prompt treatment. It is caused by congenital, idiopathic, or secondary diseases; idiopathic TTP...
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Hypertriglyceridemia-Induced Acute Pancreatitis

Park JM

Hypertriglyceridemia is a well-established cause of acute pancreatitis. The clinical presentation of hypertriglyceridemia-induced acute pancreatitis (HTG-AP) is generally not different from that of acute pancreatitis of any other etiology. There...
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A Successfully Treated Case of Recurrent Focal Segmental Glomerulosclerosis (FSGS) with Plasmapheresis and High dose Methylprednisolone Pulse Therapy

Her SM, Lee KH, Shin JI

Focal segmental glomerulosclerosis (FSGS) in children, which is a kind of nephrotic syndrome showing steroid resistance, usually progresses to a substantial number of end stage renal disease (ESRD). Although the...
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