Korean J Anesthesiol.  1981 Sep;14(3):313-318.

Malignant Hyperthermia during General Anesthesia ( A case report )

• Kim JS
• Moon JI
• Lee JH

Abstract

Malignant hyperthermia is a recently described and drmatic syndrome which rarely occurs during anesthesia, but when & dose occur is still fatal in the majority of cases with unknown etiology. It si a rypermetabolic condition characterized by tachycardia, tachypnea, skeletal muscle rigidity, respiratory and metabolic acidosis and cyanosis etc. A case is presented of a 20 year old gerveralcy healthy female with a family history of congenital eye-ild ptosis in herself as well as in all her brothers and sisters( male 2, female 4) and a generalized muscle weakness of unknown origin for several years in her father. She underwent a minor operation for correction of the congenital eyelid ptosis under N2O-O2-tachycardia developed followed by severe arrhythmia with unstable BP, minutes after induction tachycardia developed followed by sever arrhythmia with unstable BP, muscle rigiditiy and hyperpyrexia. 15 minutes after induction anesthesia was stopped and aggressive emergency treatment was atlemted. Unfortunately, she died postoperatively on the 8th day after anesthesia. Possible etiologic factors, the clinical features and management of malignant hyperthermia are discussed.

MeSH Terms

Acidosis
Anesthesia
Anesthesia, General*
Arrhythmias, Cardiac
Blepharoptosis
Cyanosis
Emergency Treatment
Fathers
Female
Humans
Male
Malignant Hyperthermia*
Muscle Weakness
Muscle, Skeletal
Siblings
Tachycardia
Tachypnea
Young Adult