Korean J Dermatol.  1992 Oct;30(5):689-692.

A case of perforating granuloma annulare

Abstract

A 29-year-old woman had multiple, umbilicated papules on her fingers for 2 months. Skin biopsy specimen showed transepidermal perforation filled with plug of cellular debris, degenerated collagen and mucinous material. In the dermis, there were necrobiosis and peripheral palisading of mononuclear cells. Special stainings including masson's trichrome, alcian blue, acid orcein, and PAS showed necrobiotic collagen fibers and acid mucopolysaccharides on the necrobiotic zone and trasepidermal elimination canal. Topical application of 0.05% Clobetasol-17-propionate ointment improved her lesion.


MeSH Terms

Adult
Alcian Blue
Biopsy
Collagen
Dermis
Female
Fingers
Glycosaminoglycans
Granuloma Annulare*
Granuloma*
Humans
Mucins
Necrobiotic Disorders
Skin
Alcian Blue
Collagen
Glycosaminoglycans
Mucins
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