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Intrawound Vancomycin Powder Application for Preventing Surgical Site Infection Following Cranioplasty

Youn SB, Hwang G, Kim HG, Kang JS, Kim HC, Oh SH, Kim MK, Chung BS, Rhim JK, Sheen SH

Objective : Surgical site infection is the most detrimental complication following cranioplasty. In other surgical fields, intrawound vancomycin powder application has been introduced to prevent surgical site infection and is...
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MST1R as a potential new target antigen of chimeric antigen receptor T cells to treat solid tumors

An W, Kang JS, Oh S, Tu A

Although chimeric antigen receptor T cell (CAR-T) is a promising immunotherapy in hematological malignancies, there remain many obstacles to CART cell therapy for solid tumors. Identifying appropriate tumor-associated antigens (TAAs)...
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Gram-Negative Bacteria’s Outer Membrane Vesicles

Kim JY, Suh JW, Kang JS, Kim SB, Yoon YK, Sohn JW

Outer membrane vesicles (OMVs) are spherical bilayered nanoparticles derived from the outer layer of Gram-negative bacteria. Bacteria communicate with nearby bacteria, their environment, and the cells of their host by...
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Reduced Cytotoxicity by Repetitive mRNA Transfection in Differentiated Neurons

Ko SH, Kang JS, Kim SM, Lee EH, Park CH

Background and Objectives: mRNA-based protein expression technology has been used to express functional proteins. We have previously generated dopamine neurons from rat-embryo derived neural precursor cells (NPCs) through repeated transfection...
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Incidence of bactibilia and related factors in patients who undergo cholecystectomy

Moon DK, Kang JS, Byun Y, Choi YJ, Lee HW, Jang JY, Lim CS

Purpose: In general, bile is normally sterile. However, there are reports bactibilia may occur in certain instances, though the causal factors are unclear. We analyzed possible preoperative predictors of bactibilia...
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Development of reverse-transcription loop-mediated isothermal amplification assays for point-of-care testing of human influenza virus subtypes H1N1 and H3N2

Kang JS, Seo MR, Chung YJ

Influenza A virus (IAV) is the most widespread pathogen causing human respiratory infections. Although polymerase chain reaction (PCR)–based methods are currently the mostcommonly used tools for IAV detection, PCR is...
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Comparisons of short-term outcomes of anastomotic methods of duct-to-mucosa pancreaticojejunostomy: out-layer continuous suture versus modified Blumgart method

Kang YH, Kang JS, Lee M, Jung HS, Yun WG, Cho YJ, Han Y, Kwon W, Jang JY

Purpose: Postoperative pancreatic fistula (POPF) is the most troublesome complication after pancreaticojejunostomy (PJ). This study aimed to compare the short-term outcomes of 2 different methods of duct-to-mucosa PJ; out-layer continuous suture...
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Results of Hip Arthroplasty Using a COREN Stem at a Minimum of Ten Years

Kang JS, Nam YC, Kwon DG, Ryu DJ

Purpose: We report on the 10-year clinical hip function and radiologic outcomes of patients who underwent hip arthroplasty using a COREN stem. Materials and Methods: A consecutive series of 224 primary...
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Comparative analysis of imaging diagnostic models for tubular basophilia and mineralization of kidney

Byun JS, Lee JH, Kang JS, Han BS

Background: Now that it is possible to efficiently classify and save tissue images of laboratory animals using wholeslide imaging, many diagnostic models are being developed through transfer learning with Convolutional...
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Effect of implant fixtures with blood pocket designed platforms on crestal bone

Kang JS, Jung BE, Ko DH, Son MK

The purpose of this study was to investigate the impact of an implant with a blood pocket designed platform on the crestal bone by analyzing the stress distribution upon simulated...
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The development and clinical efficacy of simulation training of open duct-to-mucosa pancreaticojejunostomy using pancreas and intestine silicone models

Kang JS, Sohn HJ, Choi YJ, Byun Y, Lee JM, Lee M, Kang YH, Kim HS, Han Y, Kim H, Kwon W, Jang JY

Purpose: As pancreaticojejunostomy (PJ) is a challenging anastomosis, an education program is needed to train young surgeons to perform PJ. This study evaluated the effects of simulation-based training of open...
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Predicting prognosis and evaluating the benefits of adjuvant chemotherapy depending on the tumor location in intrahepatic cholangiocarcinoma: focusing on the involvement of below 2nd bile duct confluence

Sohn HJ, Kim H, Kim JR, Kang JS, Han Y, Lee M, Kim HS, Kwon W, Hong SK, Choi Y, Yi NJ, Lee KW, Suh KS, Jang JY

Purpose: Intrahepatic cholangiocarcinoma (ICC) has various characteristics according to anatomical, histologic classifications, and its prognoses are different. This study aimed to compare oncologic outcomes according to tumor location (second bile...
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A Study of the Educational Needs of Clinical Nurses Based on the Experiences in Training Programs for Nursing COVID-19 Patients

Han JW, Joung J, Kang JS, Lee H

Purpose: This study aimed to explore the experience of clinical nurses regarding training programs for critically ill patients with coronavirus disease 2019 (COVID-19) and their educational needs. Methods: Qualitative data were...
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Deep learning approach for classification of chondrocytes in rats

Kang JS

The rapid development of computer vision and deep learning has enabled these technologies to be applied to the automated classification and counting of microscope images, there-by relieving of some burden...
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Ethanol Extract of Chaenomeles sinensis Inhibits the Development of Benign Prostatic Hyperplasia by Exhibiting Anti-oxidant and Anti-inflammatory Effects

Kang JS, Zhao XY, Lee JH, Lee JS, Keum YS

Chaenomeles sinensis is known to inhibit the development and progression of many age-related diseases, but the underlying molecular mechanisms are largely unclear. In the present study, we observed that the...
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Buerger’s Disease May be a Chronic Rickettsial Infection with Superimposed Thrombosis: Literature Review and Efficacy of Doxycycline in Three Patients

Chung MH, Lee JS, Kang JS

Buerger’s disease (BD) is a chronic inflammatory vasculitis of unknown etiology. The infectious etiology of BD was proposed by Buerger in 1914. Furthermore, there are scattered reports insisting that BD...
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Classification of Mouse Lung Metastatic Tumor with Deep Learning

Lee HN, Seo HD, Kim EM, Han BS, Kang JS

Traditionally, pathologists microscopically examine tissue sections to detect pathological lesions; the many slides that must be evaluated impose severe work burdens. Also, diagnostic accuracy varies by pathologist training and experience;...
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Comparison of oncologic outcomes of extrahepatic cholangiocarcinoma according to tumor location: perihilar cholangiocarcinoma versus distal bile duct cancer

Lee JM, Kim H, Sohn HJ, Choi YJ, Kang JS, Han Y, Kwon W, Jang JY

Purpose: Extrahepatic cholangiocarcinoma is distinguished into perihilar cholangiocarcinoma (PHC) and distal bile duct cancer (DBC). The studies for each subtype have been conducted separately. This study compared oncological outcomes between...
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In vivo study for the hemostatic efficacy and foreign body reaction of a new powder-type polysaccharide hemostatic agent

Byun Y, Kim EJ, Lee A, Suh YA, Sohn HJ, Lee JM, Kang JS, Choi YJ, Han Y, Kim H, Kwon W, Jang JY

Purpose: Various hemostatic agents have been introduced in therapy as postoperative bleeding is a poor prognostic factor for postoperative outcomes. These products can be divided into those that directly promote...
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Risk factors deteriorating severe exocrine pancreatic insufficiency measured by stool elastase after pancreatoduodenectomy and the risk factors for weight loss

Cho A, Kim H, Sohn HJ, Lee M, Kang YH, Kim HS, Han Y, Kang JS, Kwon W, Jang JY

Purpose: The measurement of stool elastase (SE) level is useful for evaluating pancreatic exocrine function. This study aimed to determine the risk factors for severe exocrine pancreatic insufficiency (EPI) after...
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