Korean Circ J.  1974 Jun;4(1):1-15. 10.4070/kcj.1974.4.1.1.

Studies on Serum Lipids Level in Normal Korean Adults and Vegetarians

Abstract

The serum lipids level of healthy Koreans, including 306 normal adults, 15 overweight persons, 25 faculty members and 40 vegetarians (monks) were studied in 1973. The following results were obtained. 1. The mean serum liplids values of normal Korean adults were 188.7+/-33.7mg% for total cholesterol, 176.9+/-47.0mg% for phospholipid and 78.0+/-28.9mg% for triglyceride. 2. It was observed that the serum level of normal Koreans were influenced only by age and were not influenced statistically by sex, weight and socioeconomic state. 3. The mean serum lipids level of Korean vegetarians (monks) were 188.0+/-44.0mg% for total cholesterol, 158.5+/-35.6mg% for phospholipid and 64.8+/-21.4mg% for triglyceride and not influenced by sex and duration of altered eating habit. 4. The serum lipids level of Korean vegetarian (monks) were significantly low in phospholipid and triglyceride but not in cholesterol. 5. No significant difference in serum total cholesterol level between normal and vegetarian were observed all the role of diet of general population were discussed.


MeSH Terms

Adult*
Cholesterol
Diet
Eating
Humans
Overweight
Triglycerides
Cholesterol

Figure

  • Fig. 1. Serum lipids level by age and sex in normal Koreans

  • Fig. 2. Comparison of serum lipids level between normal and vegetarians.


Reference

1). Anitschkow Ν.., Chalatow S.About c.r.-perimcnt Cholestin steatosis and its gnlficance for the origin of some pathological precedes. Zentrlhl. Al!g. Path. U. Path. A.nat. 1913.
2). Katz L.N.Has knozvleclge of atherosclerosis advanced sufficiently to zvarrant its appl: : ailon to a practical prevention pre gram? Circa'atlcn. 45:1972.
3). Altschule M.D.The etlclcgy of athcrosclcrccis. Med. Clin. IVorth Aj?ier. 58:397. 1974.
4). McGandy B. II., Hegsted D.M.., Stare F.J.Dietary ‘fats, carhohydrates and atherosclerotic vascular disease. Ketc Eng. J. Med. 277(186):242. 1967.
5). Zak B.., Dickenman R.C.., White E.C.., Burnet H.., Cherney P. J.Rapid estimation of free and total cholesterol. Am. J. Clin. Path. 24:1307. 1954.
Article
6). Gonnerty H.V.., Briggs A.R.., Eaton E.H. Jr.Simplified determination of the compcnents of blood scruTti. Clin. Che?7i. 7:37. 1961.
7). Van Handel E.., Zilversmit D.B.Micrcniethod for the direct determination of serum triglycerides. J. Lab. & Clin. Med. 50:152. 1957.
8). Van Handel E.Suggested modifications of the microdetermination of triglycerides. Clin. Chem. 7:249. 1961.
9). Gertler M.M.., Oppenheimer B.S.The interrelationships of serum lipids in men and women past sixty-five years of age and their bearing on atherosclercsis. Circulation. 7:533. 1953.
10). Yudkin J.Diet and. coronary thrombon hypothesis and fact. Lancet. 2:155. 1957.
11). Keys Α.., Kimura A., et al. Lessens from rcriwi cholesterol studies in Japan, Hazvaii ana Los Angels. Ann. Inter. Med. 48:83. 1958.
12). Albrink Μ J.., Man E.B.Serum triglyceride in corcnary artery disease. Arch. Int. Med. 103:4. 1959.
13). Jolliffe Ν.., Archer M.Statistical associations between international coronary heart disease, death rates and certain environmental factors. J. Chronic Dis. 9:636. 1959.
14). Antonis A.., Bersohn I.Influence of diet on serum triglycerides in South African white and Bantu prisoners. Lancet. 1:1961.
15). Cohen A.M.., Bavlv S.., Poznanski R.Changes of diet of Yemenite Jews in relation to i.: J.? CLCS a.;id lchiilc heart c.: sease. Lancet. 2:1961.
16). Bcmhn I.h: flue?ice of diet cr: S:.uth African xchuc Banlu pri: c?icrs. Ani. J,. Clin. Nutr. 1G:4S4. 1962.
17.Albrink M.J.Triglycerides, lipoproteins and coronary artery disease. Arch. Int. Med. 109:345. 1962. ,.
18). Albrink M.J.., Meigs JᅳW.., Granoff M.A.Vveight gain and serum triglycerides in normal men. New Eng. J. Med. 266:484. 1962.
19). E-Osenman R.H.., Friedman M.Behavier patterns, blood lipids, and corcnary heart disease. J.A.M.A. 184:34.
20). Yudkin J.Dietary fat and dietary c.ugar in rchiton to i: che??i: c !ι.: (ι:.ί direaac and diabetes. Lancct. 2:4. 1964.
21). Antar M.A.., Ohlson λί.Α.., Hedges R.F.Changes in retail market food supplies in United States in lcu: t seventy year. A.?n. J. Clin. Nutr. 14:169.
22). Little J.Α.., Shanoff H.M.., Csima Α.., Redmond S.E.., Yano R.Diet and serum lipids in male survivors of ?nyccard: al infarcticn. Lancet. 1:933. 1965.
23). Ραρρ O.A.., Padi I la L.., Jehnson A.L.Dietary intake in patient zvlth and zvithout fiiyocardial infarctio7i. Lancct. 2:29. 1965.
24). Brown D.F.., Kinch S.H.., Doyle J.T.Serum triglycerides in health and in ischemic heart disease. Nexv Eng. J. Med. 273:947.
Article
25). Dayton S.Pearce, M.L., Goldman, H. et al.: Controlled trial of a diet high in unsaturated fat for prevention of atherosclerotic complicatictis. Lancet. 2:1060. 1968.
26). Scrimshaw N.S.Diet and atherosclerosis. Lab. Invest. 18:63. 1968.
27). Lee K.T.., Nam S.C.., Florentin R.A.., Thomas W.A.Genesis of atherosclerosis in swine fed high fat cholesterol diets. Med. Clin. North Amer. 58:281. 1974.
28). Cornfield J.Joint dependence of risk, of coronary heart diseases on serum cholesterol and systolic hlcod pressure: A discrimi7ia7i: function analysis. Fee. :.Proc. 21:58. 1962. ,.
29). Keys Λ., et al. Coronary heart dijease among Minnesota b: isvm: s and profesicnal.:.ηαη followed fifteen yea?':. Circulatkm. 2S:3S1. 1063.
30). Kannel V.B.., Dav/ber T. R.., Friedman G.D.., Glennon W.D.., McNamara P.M.Risk factors in corcnary heart clizeo/se, evaluation of several serum lipids as predicts of corcnary heart disease: Framlngham stucly. Ann. Int. Med. 61:888. 1964.
31). Kannel W.B., et al. Vascular disease of brain. epidemiologic aspects: Framingham study. Am. J. Pub. Health. 55:1355. 1965.
32). Keys Α.., Aravanis C.., Blackburn K.W., et al. Ερ i dc m i ο legical studies related to ccrcnary dieaies: Char act e7~i sties of men aged 40-59 in seven countries. 181(Suppl 460):1966.
33). Strong J.P.., Correa P.., Solberg L.A.Water hardness and atherosclerosis. Lab. Invest. 18:620. 1968.
34). So]berg L.A.Distribution of cerebral atherosclerosis by geographic location, race and sex. Lab. Invest. 18:144. 1968.
35). Montenegro M.R.., Solberg L.A.Obesity: body ‘weight, body length and altherosclerosis. Lab. Invest. 18:594. 1968.
36). McGill H. Jr.hitroducticn to the geographic pathology of atherosclerosis. Lab. Invest. 18:465. 1968.
37). Schroeder H.A.The zvater factor. New Eng. J. Med. 280:836. 1969.
38). Texon M.Atherosclerosis: Its hemodynamic basis and implications,. Med. Clin. North Amer. 58:257. 1974.
Article
39). Zilversmit D.B.., Newman H.A.I.Does a metabolic barrier to circulating cholesterol prcicci the arterial wall. Circulation. 35:7. 1966.
40). Zernplenyi T.Vascular enzymes and the reh vance of their study to problems of atherogencsin. Med. Clin. North Amsr. 58:293. 1974.
41). Lee K.T.., jarnolych J.., Kim D.N., et al. Prcchict I.?: rf advanced coronary at hero sclcrosi 77iy'carcJai Infarct ten and u: -udcJc7i deathon szvinc. Expe? Molec. Path. 15:170. 1971.
42). .
43..
44..
46). Mario R.Raul, Costas, Jr. et al.: Interrelationship of sei-um lipids with relative weight, blood glucose and physical activity. Circulation. 45(S29):1972.
47). Hammond E.G.., Garfinke L.., Seidman H.Lcngevity of parents and grandparents in relaticn to coronary heart disease and associated variables Circulation. 43:31. 1971. ,.
48). Thomas C.B.Observation on some possible precursors of essential hypertension and coronary artry disease: V Hyper-cholesterolemia in healthy ycung adult. Am. J. Med. Sci. 232:389. 1956.
49). Basset D.R.Serum lipids in young males with parental atherosclerosis. Am. J. Med. Sci. 243:740. 1962.
50). Knittle J.L.., Ahrens E.A.J. Clin. Invest. 43:485. 1964.
51). Peterson J.E.., Keith R.A.., Wilcox A.A.Houry changes in serum cholesterol concentration: Effects of the anticipation of stress. Circulaticn. 25:798. 1962.
52). Scott M. G.Effects of periodic mental stress on serum cholesterol levels. Circulation. 19:496. 1959.
Article
53). Friedman M., et al. Changes in the serum cholesterol and blood clotting time in man subjected to cyclic variation of cccupational stress. Circulaticn. 17:852. 1958.
54). Drey fuss F.., Czazckes J.W.Blood cholesterol and uric acid of healthy medical students under the stress of an examination. Arch. Inter. Med. 203:708. 1959.
55). Friedman M.., Byers S.O.Effect of enviromental influences on alimentary lip e mi a of the rat. Amer. J. Physiol. 213:1359. 1967.
56). Nikkila E.A.., Konitinen Α.Effect of physical activity on postprandial levels in fats in serum. Lancet. 1:115. 1962.
57). Bernardis L.L.., Schnatz J.D.Localization of a hypothalamic area affecting plasma triglycerides and cholesterol levels. Diabetes. 19(βιιρρΐ):363. 1970.
58). Gutstein W.H.., Schneck D.J.Association of increazed plasma lipid levels zvith brain stimulation. Metabolism. 17:535. 1968.
59). Katz L.N., et al. Nutrition of atherosclcro. Lead & Febiger;Philadelphia: 1958.
60). Kaplan A., et al. Effect of long-lasting epinephrine on serum lipid levels. Am. J. Physiol. 191:8. 1957.
Article
61). Bergstrom S.Effect of Prostagrandin Εon plasma free fatty acids and blood glucose in the dog. Acta. Physiol. Scand. 67:141. 1966.
62). Feigelson F.B.., Pfaff W.N.., Karmen A.., Steinberg D.J. Clin. Invest. 40:2171. 1961.
63). Page I.H.., Lewis L.A.., Meinuddin M.Effect of cigarette smoking on serum cholesterol and lipoprotein concentration. J.A.M.A. 171:1500. 1959.
64). Astrup P.., Kjeldsen K.Carbon monoxidey smoking and atherosclerosis. Med. Clin. North Amer. 58:323. 1974.
65). Wald N.., Howard S.., Smith P.G., et al. Association between atherosclerotic diseases and carboccyhemoglobin levels in tobacco smokers. Brit. Med. J. 1:761. 1973.
66). Ginsberg H.Olefsky, J. and Farqubar, J.W.: Moderate ethanol ingestion and plasma triglyceride levels. A study in normal and hypertriglyceride■mic pcrso?: s. A.nn. Intern. Med. 80:143. 1974.
67). Carlson L.A.Acute effects of nicotinic acid in the rat. Acta. Med. Seand. 178:453. 1966.
68). Portman O.W., et al. Effect of dietary carbohydrate cn expe?'i?7ientary induced hyperchole stcrolemia and hyperbstalipoproteinemia in rats. Free. See. Expcr. Biol. & Med. 91:321. 1956.
69). Keys Α.., Anderson J.T.., Mickelsen O.., Adelson S. A.., Fidanza F.Diet and serum cholesterol in man. J. Nutriiion. 59:39. 1956.
70). Keys Α.., Anderson J.T.., Grande F.Serum cholesterol responses to changes in the diet. II The effect of cholesterol in the diet. Metabolism. 14:759. 1965.
71). McGandy R.B.., Hegsted D.M.., Myers M.L.., Stare F.J.Dietary carbohydrate and serum cholesterol levels in men. Am-J. Clin. Nutr. X. 8:237. 1966.
72). Siperstein M.D.., Guest M.J.Studies on the site of the feedback control of cholesterol. synthesis. J. Clin. Invest. 39:642. 1960.
73). Ahrens E.H.J. Lipid Res. 6:411. 1965.
74). Fetcher N.Anderson, J.T., Grande, F. and Keys, Α.: Quantitative estimation of diets to control serum cholesterol. Am. J. Clin. Nutr. 20:475. 1967.
75). Taylor C.B.Medical times. 95:489. 1967.
76). Keys Α.., Anderson J.T.., Grande F.Production of serum cholesterol responses of man to changes in fats in the diet. Lancet. 273:959. 1957.
77). Ahrens E.H. Jr., et al. Influence of dietary fat on serum lipid levels in man. Lancet. 1:943.
78). Kinsell L.W.., Friskey R.W.., Michaels G.D.., Splitter S.D.Essential fatty acids: lipid metabolism and atherosclerosis. Lancet. 1:334.
Article
79). Keys Α.., Anderson J.T.., Grande F.Diet-type (fats constant') and blood lipids in man. J. Nutrition. 70:257. 1960.
80). Hegsted D.M.., McGandy R.B., et al. Quantitative effects of dietary fat on serum cholesterol in man. Am. J. Clin. Nutr. 17:281. 1965.
Article
81). McGandy R.B.., Hegsted D.M.., Myers M.L.., Stare F.J.Dietary carbohydrate and seru?n cholesterol levels in man. Am. J. Clin. Nutr. 18:237. 1966.
82). McDonald I.., Braithwaite D.M.Influence of dietary carbohydrate on lipid pattern in serum and i?i adipce tissue,. Clin. Sci. 27:23. 1964.
83). Kuo P.P.., Bassett D.R.Dietary sugar in production of hyperglyceridemia. An?i. Int. Med. 62:1199. 1965.
84). Ahrens E.H.J. Clin. Invest. 43:485. 1964.
85). Levy R.I.., Less R.S.., Fredrickson D.S.The nature of pre-beta (very low density) lipoproteins. J,. Clin. Invest. 45:63. 1966.
86). Nikkila E.A.Life Sciences. 4:937. 1965.
87). Kaufmann N.A.., Poznanski R., et al. Changes in serum lipids level of hyperlipemic patient following the feeding of starch, sucrose and glucose. Am. J. Clin. Nutr. 18:261. 1966.
88). McDonald I.., Turner L.J.Serum-fructose levels after sucrose or its constituent monosaccharides. Lancet. 1:841. 1968.
89). Fallon F.J.., Kemp E.L.Effects of diet cn hepatic triglyceride. synthesis. J. Clin. Invest. 47:712. 1968.
90). Hatch F.T.Am. J. Med. 19:48. 1955.
91). Dole V. P.A relation between non-ester if led fatty acids in plasma and the metabolism of. glucose. J. Clin. Invest. 35:150. 1956.
92). Reaven G.M., et al. Kinetics of triglyceride turnover of very low density Upoprctsin of human. plasma. J. Clin. Invest. 44:1826. 1965.
93). Farquhar J.W., et al. Glucose, insulin, and triglyceride responce to high and low carbohydrate diets in. man. J. Clin. Invest. 45:1648. 1966.
94). Salans L.B.Proc. See. Exp. Bid. Med. 122:1208. 1966.
95). 申鼓求. 韓國ᄉ의血淸a, β-lipoprctein cholesterol 量에對하여洋食韓國ᄉ및a韓美軍人의그것과의比較. 韓國露學. 2:61. 1959.
96). 金基焕. 韓國正常人및動脈硬化症患者에있어서의血淸에關한臨床的觀察. 最新醫學. 3:51. 1960.
57). 李迎兩. 正常ᄉ및各S疾患에서의血淸脂質에關한研究. ᄎ韓內科學會雜誌. 13:303. 1970.
98). 김창연. 최제하. 김기환. 韓國정상인및각종질환군의혈청cAo/aieroZ 에대한임상적관찰. 대한내과학회잡지Ϊ. 3:85. 1970.
99). Carlson L. Α.Serum lipids in normal man. Acta. Med. Scand. 167:377. 1960.
100). Lund L.Silvertssen, E. and Godal, H.C.: Studies on serum lipids. I Healthy individuals. Acta. Med. Scand. 169:623. 1961.
101). Svanborg A.., Svennerholm L.Plasma lipids, cholesterols'triglycerides, phospholipids and free fatty acids in a healthy Scandinavian population. Acta. Med. Scand. 169:43. 1361.
102). Stafford W.L.Lipid metabolism. A companion of medical studies. Ed. Passmore, R.F.A. Davis camp. Phladelphia Pa.1968.
103). 보건사업평가조사예비조사보고力. 188. 1961.
104). 한국의과학연구소. 한국인이식품영양조사(제1 보). 한국의과학. 1:737. 1969.
105). 한국의과학연구소. 한국인의식품영양조사C제2보): ᄎ외kl. 네1973.
016). 五島雄一郞. 脂質代謝異常©臨束: 南山堂: 東京. 1972.
107). Chong Υ. Η.., Soh C.C., et al. Serum low density lipoproteins, triglycerides and cholesterol levels in Malaysia. Clin. Chim. Acta. 34:85. 1971.
108). Passmore R.Essential materials and waste. A companion to medical studies. Ed. Passmore, R. F.A. Davis Comp. Philadelphia. Pa.1968.
109). Ahrens E.H.J. Ass. Am. Physic. 74:134. 1961.
110). Fredrickson D.S.., Levy R.I.., Lee R.S.Fat transport in lipoprotein. An integrated approach to mechanisms and disorders. New Eng. J. Med. 276:34. 94, 148, 215, 27 3. 1967.
111). Hardinge M.G.., Stare F.J.Nutritional studies of vegetarians: Dietary and serum levels of. cholesterol. J. Clin. Nutr. 2:283. 1954.
112). Hardinge M.G.., Crooks H.., Stare F.J.Nutritional studies of vegetarians: IV Dietary Fatty acids and serum, cholesterol levels. Am. J. Clin. Nutr. 10:516. 1962.
113). Hardinge M.G.Nutritional studies of vegetarians. J. Amer. Diet. Λ. 48:258. 1966.
Article
114). Chen J.S.The effect of long term vegetable diet 07i serum lipid and lipoprotein levels in man. J. Formosan. Med. Ass. 65:65. 1966.
115). Kirkeby K.Blood lipids, lipoproteins, and proteins in vegetarians. Acta Med, Scand. 443(Suppl):1–84. 1966.
116). Scott R.F.., Lee K.T.., Kim D.N., et al. Fatty acids of serum and adipose tissue in six groups eating natural diets containing 7-40 per cent fat:. Am. J. Clin, Nutr. 14:280. 1964.
117). 徐舜圭等. 韓國ᄉ의標準體重値. 대한내과학회잡지. 14:699. 1971.
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