J Rheum Dis.
2012 Apr;19(2):91-94. 10.4078/jrd.2012.19.2.91.
A Case of Acute Myeloid Leukemia after Adalimumab Treatment in Psoriatic Arthritis
- Affiliations
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- 1Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, School of Medicine, The Catholic University of Korea, Seoul, Korea. rapark@catholic.ac.kr
- 2Division of Rheumatology, Department of Internal Medicine, Bucheon St. Mary's Hospital, School of Medicine, The Catholic University of Korea, Bucheon, Korea.
- KMID: 2223106
- DOI: http://doi.org/10.4078/jrd.2012.19.2.91
Abstract
- Hematologic malignancies and lymphoproliferative disorders have been reported after using tumor necrosis factor-alpha inhibitor in patients suffering from spondyloarthropathy. Previously reported cases were treated by using infliximab and etanercept. Usually, it takes approximately several months for leukemia or lymphoproliferative disorders to occur after the application of those agents. However, we report a case of acute myeloid leukemia that developed after short term usage of adalimumab in a patient suffering from psoriatic arthritis.
MeSH Terms
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Antibodies, Monoclonal
Antibodies, Monoclonal, Humanized
Arthritis, Psoriatic
Hematologic Neoplasms
Humans
Immunoglobulin G
Leukemia
Leukemia, Myeloid, Acute
Lymphoproliferative Disorders
Receptors, Tumor Necrosis Factor
Spondylarthropathies
Stress, Psychological
Tumor Necrosis Factor-alpha
Adalimumab
Infliximab
Etanercept
Antibodies, Monoclonal
Antibodies, Monoclonal, Humanized
Immunoglobulin G
Receptors, Tumor Necrosis Factor
Tumor Necrosis Factor-alpha
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