J Korean Ophthalmol Soc.  2015 Jan;56(1):25-32. 10.3341/jkos.2015.56.1.25.

Changes of Higher Order Aberration Analyzed by Continuous Measurement after Phacoemulsification

• Lim HB
• Lee JJ
• Choi SH

• KMID: 2216150
• DOI: http://doi.org/10.3341/jkos.2015.56.1.25

Abstract

PURPOSE
To analyze the changes of higher order aberration (HOA) measured serially by KR-1W(R) wavefront at every second for 10 seconds between, before, and after phacoemulsification and to evaluate the relationships between HOA and the ocular surface indicators (Schirmer test, tear break-up time, superficial punctate keratitis).
METHODS
Corneal HOA was measured in 47 eyes of 30 patients pre- and postoperatively at 2, 4, 6, and 8 weeks by KR-1W(R) using the continuous measurement mode. The patients were divided into 2 groups according to their Schirmer test (above 10 mm or under 10 mm), tear break-up time (above 5 seconds or less than 5 seconds), and superficial punctate keratitis (any keratitis, none) for analysis of relationships between HOA and ocular surface indicators, and we also analyzed the correlation coefficient.
RESULTS
Short-term follow up after phacoemulsification revealed that corneal HOA rapidly increased at 2 weeks and recovered to the preoperative level 8 weeks after surgery. Corneal HOA values showed increasing tendency depending on time at preop and 8 weeks after phacoemulsification, and the differences were statistically significant (preop: p < 0.001, 8 weeks: p = 0.027). There were no significant differences of HOA between the 2 groups divided according to their ocular surface indicators, and there were no significant correlations between HOA and ocular surface indicators at any time point.
CONCLUSIONS
The HOA of the cornea was restored to its preoperative values at 8 weeks after surgery. Preoperative ocular surface indicators are not significantly influenced on postoperative corneal HOA. The surgical factors are more significant in postoperative corneal HOA than preoperative ocular surface indicators.

Keyword

Higher order aberration; Phacoemulsification

MeSH Terms

Cornea
Follow-Up Studies
Humans
Keratitis
Phacoemulsification*
Tears

Figure

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  Figure 1. Continuous measurement mode using KR-1W Ⓡ wavefront analyzer. HOA = higher order aberration; RMS = root mean square.

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  Figure 2. Serial changes in corneal higher order aberration (HOA) over time. Short-term follow up after pha-coemulsification reveals that corneal HOA recovers to the preoperative level at 8 weeks after surgery. RMS = root mean square. * p < 0.05; p-value from repeated measure ANOVA.

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  Figure 3. Changes of corneal higher order aberration (HOA) between 1 and 10 seconds after blinking. Corneal HOA of the 1 and 10 seconds are both similarly high on the 2 weeks after surgery, however, as time passed to 4th, 6th, and 8th weeks, as like before surgery, values show increasing tendency depending on time. * p < 0.05; p-value from paired t-test.

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  Figure 4. Serial changes in ocular surface indicators. All factors recovered to preoperative levels at 8 weeks after surgery. SPK = superficial punctate keratitis; BUT = break up time. * p < 0.05; p-value from repeated measure ANOVA.

Reference

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