J Korean Ophthalmol Soc.  2012 Jan;53(1):111-119. 10.3341/jkos.2012.53.1.111.

Relationship between Preoperative Biometry and Intraocular Pressure Reduction after Phacoemulsification in Normal and Glaucoma Patients

• Park S
• Lee M
• Ahn J

• KMID: 2215252
• DOI: http://doi.org/10.3341/jkos.2012.53.1.111

Abstract

PURPOSE
To investigate the relationships between preoperative factors and intraocular pressure (IOP) reduction after phacoemulsification in normal, open-angle glaucoma (OAG) and angle-closure glaucoma (ACG) patients.
METHODS
IOP was measured before and 3 months after cataract surgery in 30 normal, 24 OAG and 31 ACG patients. The relationship between IOP reduction after cataract surgery and preoperative parameters including anterior chamber depth (ACD), axial length (AL), preoperative IOP/ACD ratio (PD ratio), preoperative IOP/AL ratio (PL ratio) were investigated in the 3 groups.
RESULTS
Significant IOP reduction was observed in all 3 groups after surgery (paired sample t-test; p < 0.05), and IOP reduction was correlated with preoperative IOP level in all 3 groups (Pearson's correlation; p < 0.05). Other preoperative parameters such as ACD and AL were not correlated with IOP reduction, and PD ratio was significantly correlated with IOP reduction only in the OAG group (Pearson's correlation; p < 0.001). PL ratio was significantly correlated with IOP reduction in all 3 groups (Pearson's correlation; p < 0.05) and showed the best sensitivity and specificity to predict significant reduction in IOP after cataract surgery among parameters including preoperative IOP, PD ratio and PL ratio.
CONCLUSIONS
PL ratio was significantly correlated with IOP reduction after cataract surgery in all 3 groups and showed a higher predictive value for IOP reduction in the OAG group than in the other groups.

Keyword

Anterior chamber depth; Axial length; Intraocular pressure; Phacoemulsification; Predictive value

MeSH Terms

Anterior Chamber
Biometry
Cataract
Glaucoma
Glaucoma, Angle-Closure
Glaucoma, Open-Angle
Growth Hormone
Humans
Intraocular Pressure
Peptide Fragments
Phacoemulsification
Sensitivity and Specificity
Growth Hormone
Peptide Fragments

Figure

• 

  Figure 1 AU-ROC curve of preoperative IOP, PD ratio, PL ratio to predict at least 4 mm Hg IOP reduction after cataract surgery (A: Total; B: Normal group; C: OAG group; D: ACG group). AU-ROC of the PD ratio was smaller than that of preoperative IOP and PL ratio in total, normal and ACG groups (A, B, D). AU-ROC of OAG group was larger than that of normal and ACG groups (C). AU-ROC of the PD ratio was larger than that of preoperative IOP and PL ratio in OAG group (C). OAG = open-angle glaucoma; ACG = angle-closure glaucoma; AU-ROC = area under-receiver operating characteristics; Preop IOP = preoperative intraocular pressure; PD ratio = pressure/depth ratio; PL ratio = pressure/length ratio.

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