J Korean Ophthalmol Soc.  2015 Oct;56(10):1624-1629. 10.3341/jkos.2015.56.10.1624.

A Retrospective Study of Choroidal Thickness in Children with Unilateral High Myopia

• Cho YW
• Kim CR
• Yoo WS
• Yoo JM

• KMID: 2214425
• DOI: http://doi.org/10.3341/jkos.2015.56.10.1624

Abstract

PURPOSE
To compare the choroidal thickness of unaffected and affected eyes in children with unilateral high myopia when measured using enhanced depth imaging and to analyze the relationship among choroidal thickness and axial length, spherical equivalent and best corrected visual acuity (BCVA).
METHODS
Twenty children with high unilateral high myopia who received optical coherence tomography from December 2012 to May 2014 were retrospectively analyzed. Choroidal thickness was measured with a caliper at 500 microm apart from fovea superiorly and inferiorly, 2,500 microm apart nasally and at 2,500 microm apart temporally at 500 microm intervals. For statistical analyses, paired t-test was used for choroidal thickness and linear regression analysis for the relationship among choroidal thickness and axial length, spherical equivalent and BCVA.
RESULTS
The patients were 10.4 +/- 3.5 years of age and the average BCVA of myopic eye was 0.38 +/- 0.2. Mean spherical equivalent was -9.8 +/- 1.9D. The choroidal thickness was significantly thinner in the myopic eye (102.5 +/- 16.9 microm) than the fellow eye (282.9 +/- 14.0 microm). The thickest choroid in the myopic eye was the temporal and the thinnest was the nasal area (p = 0.008). Choroidal thickness was significantly associated with axial length and spherical equivalent but not BCVA.
CONCLUSIONS
Highly myopic eyes tend to have thinner choroidal thickness than the fellow eyes and choroidal thickness tends to be thicker temporally. Therefore, several anatomical changes in unilateral highly myopic children may exist.

Keyword

Choroidal thickness; Enhanced depth imaging; Unilateral high myopia

MeSH Terms

Child*
Choroid*
Humans
Linear Models
Myopia*
Retrospective Studies*
Tomography, Optical Coherence
Visual Acuity

Figure

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  Figure 1. Measurements of choroidal thickness in normal (A) and high myopic eye (B) using enhanced depth imaging. Choroidal thickness was measured by calipers at 500 μm apart from the fovea superiorly and inferiorly, from 2,500 μm apart nasally and to 2,500 μm apart temporally with 500 μm intervals.

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  Figure 2. Choroidal thickness of the myopic eye and the fellow eye graph shows the choroidal thickness in the myopic eye and the fellow eye. Mean thickness at each of the 11 locations measured by 500 μm intervals from temporal (T5) to the nasal (N5) including the subfoveal area. The thickest choroid in the fellow eye (top) is in the subfoveal area, and the thickest choroid in the myopic eye (bottom) is in the temporal area. T = temporal; N = nasal.

Reference

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