J Korean Ophthalmol Soc.  2009 May;50(5):677-683. 10.3341/jkos.2009.50.5.677.

Long-term Change in Corneal Endothelium After Iris-fixed Phakic Intraocular Lens Insertion

• Kim SE
• Hong SM
• Lee HK

• KMID: 2212297
• DOI: http://doi.org/10.3341/jkos.2009.50.5.677

Abstract

PURPOSE:To investigate long-term endothelial changes in phakic eyes implanted with iris-claw phakic intraocular lens (IOL) (Artisan(R) lens Ophtec, Groningen, Netherlands) and to identify the associated factors.
METHODS
Thirty-one eyes of 18 patients underwent Artisan phakic IOL implantation and were followed up for over 1 year. The authors retrospectively examined the endothelial cell density, percentage of hexagonal cells and coefficient of variation using the result of non-contact specular microscope.
RESULTS
The mean endothelial cell loss was 0.9% at 23.9+/-9.44 months of the mean follow-up period. There was no statistically significant decrease in endothelial cell density (p=0.445). There was no statistically significant change in pleomorphism and polymegathism of the endothelial cells after the surgery. There was no statistically significant correlation between endothelial cell loss and anterior chamber depth (r2=0.0488, p=0.377).
CONCLUSIONS
No clinically significant endothelial damage occurred after iris-claw phakic IOL implantation. However, special attention should be given to patients with shallow anterior chamber depth for iris-claw phakic IOL insertion to avoid unintended endothelial damage and long-term endothelial checkups using a specular microscope are critical for long-term protection of endothelial cells.

Keyword

Corneal endothelial cell; Iris-claw phakic intraocular lens; Myopia

MeSH Terms

Anterior Chamber
Endothelial Cells
Endothelium, Corneal
Eye
Follow-Up Studies
Humans
Myopia
Phakic Intraocular Lenses
Retrospective Studies

Figure

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  Figure 1. Changes in endothelial cell density (ECD).

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  Figure 2. Changes in coefficient of variation (CV) of endothelial cells.

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  Figure 3. Changes in frequency of hexagonal cells (6A).

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  Figure 4. Determination of correlation coefficient between anterior chamber depth and endothelial cell loss (pre-operative endothelial cell density [ECD]-postoperative ECD) per patient (n=31).

Reference

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