J Korean Ophthalmol Soc.  2015 Jul;56(7):1020-1027. 10.3341/jkos.2015.56.7.1020.

Clinical Outcomes of Foldable Iris-Fixed Phakic Intraocular Lens and Change in Corneal Endothelial Cell Density

• Seong S
• Choi CM
• Choi TH
• Kim SK

• KMID: 2148801
• DOI: http://doi.org/10.3341/jkos.2015.56.7.1020

Abstract

PURPOSE
To evaluate the efficacy, safety, stability and complications of the foldable iris-fixated phakic intraocular lens (Artiflex(R), Ophtec BV, Groningen, Netherlands) implantation for the correction of myopia with astigmatism.
METHODS
The present study included 40 eyes of 20 patients who underwent Artiflex lens implantation, and 20 eyes of 10 patients who underwent Toric Artiflex lens implantation and were followed up for 1 year. We retrospectively examined visual acuity, refraction, any changes in astigmatism, efficacy, safety and corneal endothelial cell density. A correlation coefficient analysis of the factors that affected the changes was performed.
RESULTS
The mean preoperative refractive spherical equivalent was -9.18 +/- 2.27 D and reached -0.45 +/- 0.45 D at 1 year after surgery. Postoperatively, 99.9% of the eyes showed improved visual acuity of more than 0.8. In patients with Toric Artiflex lens implantation, the preoperative mean astigmatism was -2.67 +/- 0.87 D, and at 1 year postoperatively -0.76 +/- 0.40 D, showing a statistically significant decrease (p < 0.001). The preoperative mean endothelial cell density was 2,850 +/- 230 cells/mm2 and decreased 1.3% on the final follow-up (2,812 +/- 261 cells/mm2) but without statistical significance (p = 0.456). Statistically significant correlation was not observed between endothelial cell loss and anterior chamber depth (r2 = -0.146, p = 0.267).
CONCLUSIONS
Implantation of the iris-fixed intraocular lenses, Artiflex and Toric Artiflex, was safe and effective for correcting high myopia and astigmatism.

Keyword

Artiflex; Foldable; Intraocular lens; Iris-fixed; Toric artiflex

MeSH Terms

Anterior Chamber
Astigmatism
Endothelial Cells*
Follow-Up Studies
Humans
Lenses, Intraocular
Myopia
Phakic Intraocular Lenses*
Retrospective Studies
Visual Acuity

Figure

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  Figure 1. Efficacy. Postop = postoperation; UDVA = un-corrected distance visual acuity; Preop = preoperation; CDVA = corrected distance visual acuity.

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  Figure 2. Preoperative and postoperative spherical equivalent.

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  Figure 3. Stability: time course of manifest spherical equiv-alent after operation.

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  Figure 4. Preoperative and postoperative refractive astigmatism.

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  Figure 5. Postoperative changes in endothelial cell density.

Reference

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