J Korean Surg Soc.  2010 Mar;78(3):192-194. 10.4174/jkss.2010.78.3.192.

Mediastinum Anthracosis Resembling Metastatic Carcinoma from Thyroid Gland

Affiliations
  • 1Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. surghsc@yuhs.ac
  • 2Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Abstract

The differential diagnosis of mediastinal lymph node enlargement is mandatory, since the diagnosis of mediastinal lymph node enlargement covers a broad spectrum of diseases including inflammatory reactions, infections, and cancer metastases. We describe here a 51-year-old woman with anthracosis in mediastinal lymph node, mimicking metastatic carcinoma from the thyroid gland.

Keyword

Anthracosis; Mediastinum; Papillary thyroid carcinoma; Metastasis

MeSH Terms

Anthracosis
Carcinoma
Diagnosis, Differential
Female
Humans
Lymph Nodes
Mediastinum
Middle Aged
Neoplasm Metastasis
Thyroid Gland
Thyroid Neoplasms
Carcinoma
Thyroid Neoplasms

Figure

  • Fig. 1 Cervical ultrasonography (A) and computed tomography (B) showing ill-defined, heterogeneous, large mass in the right supraclavicular fossa (CCA = common carotid artery; IJV = internal jugular vein).

  • Fig. 2 Histopathologic findings of lymph node. The lymph node was revealed as reactive lymphoid hyperplasia and diffuse anthracosis (H&E, ×12.5). The pigmented area revealed many macrophages containing dark brown granular anthracotic pigment (inset; H&E, ×400).


Reference

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