J Korean Pediatr Soc.
1997 Nov;40(11):1537-1543.
Comparison of Antimicrobial Susceptibility of Nosocomial and Community-Acquired Pathogens in Children of Medium-Sized Hospital
- Affiliations
-
- 1Department of Pediatrics, College of Medicine, Hallym University, Seoul, Korea.
- 2Department of Clinical Pathology, College of Medicine, Hallym University, Seoul, Korea.
Abstract
- PURPOSE
We evaluated the identification and antimicrobial susceptibility patterns of nosocomial and community-acquired pathogens in children of the medium-sized hospital.
METHODS
The 357 bacterial strains isolated from Pediatric department of Dongsan Sacred Heart Hospital were examined the species identification and antimicrobial susceptibility test during the period of March to October 1996.
RESULTS
Fifty three strains (15%) of 357 strains were nosocomial pathogens. A half of Enterococcus faecium is nosocomial pathogens. As a rule, Antimicrobial resistance of nosocomial pathogens were higher than those of community-acquired pathogens. Enterococcus sp. isolated from nosocomial infection were significantly less susceptible than those from community-acquired infection to imipemem (P<0.05). Escherichia coli isolated from nosocomial infection were significantly less susceptible than those from community-acquired infection to amoxicillin/clavulanate, cefuroxime, cefoxitin, ceftazidime, and aztreonam (P<0.05). Klebsiella pneumoniae isolated from nosocomial infection were significantly less susceptible than those from community-acquired infection to cephalothin, cefuroxime, cefotaxime, aztreonam, tobramycin, gentamicin, and co-trimoxazole (P<0.05).
CONCLUSIONS
In medium-sized hospital, the rate of antimicrobial resistance to nosocomial pathogens was higher than community-acquired pathogens. The regular reports of the susceptibility patterns of nosocomial and community-acquired pathogens would be useful to improve the effects of empirical antimicrobial therapy.
MeSH Terms
-
Aztreonam
Cefotaxime
Cefoxitin
Ceftazidime
Cefuroxime
Cephalothin
Child*
Community-Acquired Infections
Cross Infection
Enterococcus
Enterococcus faecium
Escherichia coli
Gentamicins
Heart
Humans
Klebsiella pneumoniae
Tobramycin
Trimethoprim, Sulfamethoxazole Drug Combination
Aztreonam
Cefotaxime
Cefoxitin
Ceftazidime
Cefuroxime
Cephalothin
Gentamicins
Tobramycin
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