J Korean Pediatr Soc.  2000 May;43(5):632-637.

Isolation of Causative Microorganism and Antimicrobial Susceptibility Test in Impetigo Developed in the Past Four Years

• Lee HJ
• Lee SJ
• Ha SJ
• Oh CK
• Kim JW

Abstract

PURPOSE: Recently, Staphylococcus aureus has been reported as the principal microorganism isolated from impetigo, showing variable degrees of antimicrobial resistance. The aim of this work was to study the causative organism of impetigo the their antimicrobial susceptibility developed in impetigo in the past four years.
METHODS
We performed bacterial cultures and antimicrobial susceptibility tests in 73 patients with impetigo who visited the Department of Dermatology and Pediatrics at St. Paul's Hospital of the Catholic University of Korea in Seoul.
RESULTS
Of 73 patients, microorganisms were identified in 70 patients between May 1995 and August 1999. Staphylococcus aureus was isolated from 63 (90%) patients. Antimicrobial susceptibility test for Staphylococcus aureus revealed low resistance to bactrim (0.0%), rifampicin (0.0%), van- comycin (3.2%), ceftriaxone (4.0%), imipenem (5.4%), ampicillin-clavulanic acid (6.1%), oxacillin (8.1%), cephazolin(9.1%), cephalothin (9.7%) and cefotaxime (10.8%). However, Staphylococcus aureus had high resistance to erythromycin (65.7%) and gentamicin(85.5%). Thirty-six (57.1%) strains of isolated Staphylococcus aureus showed resistance to more than one drug, including two strains (3.1%) resistant to more than 10 drugs.
CONCLUSION
Staphylococcus aureus was the most common cause of impetigo developed in the pa- st four years. It was susceptible to most antimicrobial agents except erythromycin and gentamicin, and methicillin resistance was not strong in our results.

Keyword

Bacterial culture and sensitivity test; Impetigo; Staphylococcus aureus

MeSH Terms

Anti-Infective Agents
Cefotaxime
Ceftriaxone
Cephalothin
Dermatology
Erythromycin
Gentamicins
Humans
Imipenem
Impetigo*
Korea
Methicillin Resistance
Oxacillin
Pediatrics
Rifampin
Seoul
Staphylococcus aureus
Trimethoprim, Sulfamethoxazole Drug Combination
Anti-Infective Agents
Cefotaxime
Ceftriaxone
Cephalothin
Erythromycin
Gentamicins
Imipenem
Oxacillin
Rifampin