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External Validation of a Pharmacokinetic Model of Propofol for Target-Controlled Infusion in Children under Two Years Old

Ji SH, Lee JH, Cho JY, Kim HS, Jang YE, Kim EH, Kim JT, Kim HS

BACKGROUND: Previously, a linked pharmacokinetic-pharmacodynamic model (the Kim model) of propofol with concurrent infusion of remifentanil was developed for children aged 2–12 years. There are few options for pharmacokinetic-pharmacodynamic model...
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Long-Term Efficacy of Anti-Tumor Necrosis Factor Agents in Pediatric Luminal Crohn's Disease: A Systematic Review of Real-World Evidence Studies

van Rheenen H, van Rheenen PF

PURPOSE: To determine the long-term efficacy of the anti-tumor necrosis factor (TNF) agents, infliximab (IFX) and adalimumab (ADA), in pediatric luminal Crohn's disease (CD) by performing a systematic literature review. METHODS:...
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Association of vitamin D deficiency with clinical outcomes in critically ill Korean children

Jhang WK, Kim DH, Park SJ

BACKGROUND/OBJECTIVES: Vitamin D is a pleiotropic hormone that affects various body organ systems. We evaluated the prevalence of a vitamin D deficiency (VDD) and its potential role in the clinical...
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The diagnostic usefulness and correlation of nasal eosinophil count and percentage in children with rhinitis

Yoon KH, Kim K, Yoon JS, Kim HH

PURPOSE: Allergic rhinitis is the most common atopic disease and the most common chronic disease of children. Eosinophil count and percentage in nasal smear are useful for differential diagnosis of...
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A Comparative Analysis of Clinical Screening Test and Language Specific Test in Language Delay Children

Lee NR, Chung SH, Song MK, Kong YH, Joo CU, Kim SJ

The aim of this study was to investigate the usefulness of a clinical screening test [the Korean Infant and Child Developmental Test (KICDT)] compared to language specific tests: the sequenced...
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Clinical and Laboratory Findings of Barley Allergy in Korean Children: a Single Hospital Based Retrospective Study

Lee E, Jeong K, Lee J, Jeon SA, Park B, Lee H, Lee S

BACKGROUND: Barley is a grain that is consumed in various forms in Asia. Studies on barley allergy are limited to a few case reports about hypersensitivity reactions to beer, but...
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Gastric Xanthoma in the Pediatric Population: A Possible Herald for Malignancy?

Russell JD, Peck J, Phen C, Linehan JL, Karjoo S, Nguyen J, Wilsey MJ

Gastric xanthoma is frequently an incidental finding on upper endoscopy in adults. Gastric xanthomas (GX) can be mistaken for malignancies and warrant prompt histologic diagnosis. The underlying etiology is not...
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Korean Children and Adolescents with Crohn's Disease Are More Likely to Present with Perianal Fistulizing Disease at Diagnosis Compared to Their European Counterparts

Kang B, Kim JE, Jung JH, Choe JY, Kim MJ, Choe YH, Kim S, Koh H, Lee YM, Lee JH, Lee Y, Lee JH, Lee HJ, Jang HJ, Choi Y, Choi SY, Kim JY, Choe BH

PURPOSE: We aimed to investigate the disease phenotype of Korean pediatric Crohn's disease (CD) patients at diagnosis according to the Paris classification by comparison with patients from the European multicenter...
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Focal Cortical Dysplasia in Pediatric Epilepsy

Choi SA, Kim KJ

Focal cortical dysplasia (FCD) is the most common cause of intractable focal epilepsy in children undergoing epilepsy surgery. In these patients, seizures usually develop in early childhood and are often...
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Comparative Analysis of Prescription for Splitted Tablet using the HIRA-NPS (Health Insurance Review & Assessment Service-National Patient Sample)

Kwon HJ, Jang KW, Ha D

OBJECTIVE: The aim of this study was to analyze the status of split tablet prescription in South Korea. METHODS: We conducted this analysis using 2016 National Patient Sample data from the...
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Clinical Usefulness of Neutrophil-Lymphocyte Ratio as a Predictor of Henoch–Schönlein Nephritis

Kim M, Suh WS

OBJECTIVE: Henoch–Schönlein purpura is the most widespread systemic vasculitis during childhood. This study evaluated the relationship between neutrophil-lymphocyte ratio (NLR) and Henoch–Schönlein nephritis, which is important for the long-term prognosis...
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Analysis of Compliance and Clinical Outcomes by Expanding Physician's Departments in Pediatric Nutrition Support Team

Lee HW, Jung MJ, Park JE, Kwon H, Kim JS, Go H, Son ES

PURPOSE: Malnutrition in hospitalized children has an impact on growth, morbidity, and mortality. For this reason, the implementation of pediatric nutrition support team (PNST) has been suggested. On April 2017,...
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The effect of introducing Pediatric Emergency Care Applied Research Network rule on reducing brain computed tomography use for children with minor head injury

Jung SW, Jang JH, Cho JS, Hyun SY, Lim YS, Yang HJ, Choi JY

PURPOSE: Computed tomography (CT) scan is an effective modality for detecting fatal traumatic brain injury. However, radiation exposure from CT can increase the risk of cancer, and children are more...
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Prediction for serious bacterial infection in febrile children aged 3 years or younger: comparison of inflammatory markers, the Laboratory-score, and a new laboratory combined model

Kim YW, Kyong YY, Choi KH, Choi SM, Oh YM, Oh JS, Oh SH, Park JT

PURPOSE: To compare the efficacy of inflammatory markers, the Laboratory-score, and a new laboratory combined model for predicting serious bacterial infection (SBI) in young febrile children. METHODS: The presence of SBI...
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A Study on Factors Associated with Duration of Influenza Virus Shedding in Children

Oh SR, Son BH, Lee KW

To prevent the spread of influenza among infants and adolescents attending kindergartens and schools, proper quarantining of those who are ill is necessary. In this study, the rapid antigen test...
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A Study on Factors Associated with Duration of Influenza Virus Shedding in Children

Oh SR, Son BH, Lee KW

To prevent the spread of influenza among infants and adolescents attending kindergartens and schools, proper quarantining of those who are ill is necessary. In this study, the rapid antigen test...
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A Study on Factors Associated with Duration of Influenza Virus Shedding in Children

Oh SR, Son BH, Lee KW

To prevent the spread of influenza among infants and adolescents attending kindergartens and schools, proper quarantining of those who are ill is necessary. In this study, the rapid antigen test...
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Basics of continuous renal replacement therapy in pediatrics

John JC, Taha S, Bunchman T

In the last three decades, significant advances have been made in the care of children requiring renal replacement therapy (RRT). The move from the use of only hemodialysis and peritoneal...
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Current status of long-term antibiotic prophylaxis for urinary tract infections in children: An antibiotic stewardship challenge

Alsubaie S, Barry MA

Recurrent urinary tract infections (UTIs) in children are associated with development of pyelonephritis and renal scarring. Traditionally, continuous antibiotic prophylaxis (CAP) has been used to prevent recurrent UTI. Recent studies...
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Epidemiology of Burns in Infants: A Four-Year Retrospective Study

Yu HH, Choi Y

PURPOSE: Little information has been published regarding minor burn injuries in infants, most of which are preventable. To fill this research gap, this study explored the patterns and mechanisms of...
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