J Korean Ophthalmol Soc.  1988 Apr;29(2):331-335.

Extracellular Matrix of the Cultured Retinal Pigment Epithelial Cells

• Ko MK
• Choe JK

Abstract

This study was undertaken in an attempt to localize fibronectin and collagen type IV to the cultured retinal pigment epithelial cell by means of immunofluorescent staining and immunocytochemrcal method. Immunofluorescent staining and immunocytochemical methcds revealed fibronectin and collagen type IV localized on the extracellular membrane of the cultured retinal pigment epithelial cell. Ultrastructural immunocytochemical technique also revealed fibronectin associated with extracellular tissue. This study demonstrated that fibronectin and collagen type IV are an integral component of the extracellular matrix of the retinal pigment epithelial cell in vitro.

MeSH Terms

Collagen Type IV
Epithelial Cells*
Extracellular Matrix*
Fibronectins
Membranes
Retinaldehyde*
Collagen Type IV
Fibronectins
Retinaldehyde