J Korean Rheum Assoc.
2004 Dec;11(4):433-436.
A Case of Colchicine-induced Acute Myopathy in a Renal Recipient
- Affiliations
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- 1Departments of Internal Medicine, Inje University College of Medicine, Seoul, Korea. chanheel@unitel.co.kr
- 2Departments of Pathology, Inje University College of Medicine, Seoul, Korea.
Abstract
- Colchicine is one of the most effective drugs for the treatment of acute gouty arthritis. It can cause myopathy which may be diagnosed by abnormalities of muscle enzyme levels, electromyography, and muscle biopsy, and disappearance of symptoms after drug withdrawal. Colchicine-induced myopathy may be seen in patients with unusually high dose of colchicine, renal insufficiency, combination therapy with cyclosporin, and advanced age. We report a patient who developed acute myopathy after treatment with colchicine for gout which was associated with renal transplantation and cyclosporin treatment.
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