J Korean Rheum Assoc.  2010 Jun;17(2):188-193. 10.4078/jkra.2010.17.2.188.

A Case of Diffuse Muscular Calcification following Necrotizing Cutaneous Vasculitis in a Patient with Dermatomyositis

• Kim BR
• Lee HS
• Lee YH
• Harn SW
• Munkhdelger J
• Cho MY
• Kang TY

• KMID: 2201970
• DOI: http://doi.org/10.4078/jkra.2010.17.2.188

Abstract

Dermatomyositis is a systemic connective tissue disease affecting the skeletal muscles and skin. Necrotizing cutaneous vasculitis and subsequent diffuse subcutaneous and muscular calcification in patients with dermatomyositis is uncommon and has not been reported. A 23-year-old female with dermatomyositis developed necrotizing cutaneous vasculitis in the knee, elbow, buttock, toe and fingers associated with large ulcer formation. Her left 5th finger was amputated due to massive soft tissue destruction, and her right 5th finger later auto-amputated. Thereafter, she developed small subcutaneous nodules on both wrists, elbows, upper arms, neck, buttocks and thighs. X-ray, computerized tomography and gracilis muscle biopsy confirmed diffuse subcutaneous, fascia and muscular calcifications.

Keyword

Dermatomyositis; Diffuse muscular calcification; Necrotizing cutaneous vasculitis

MeSH Terms

Arm
Biopsy
Buttocks
Connective Tissue Diseases
Dermatomyositis
Elbow
Fascia
Female
Fingers
Humans
Knee
Muscle, Skeletal
Muscles
Neck
Skin
Thigh
Toes
Ulcer
Vasculitis
Wrist
Young Adult

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