J Korean Radiol Soc.  1998 Mar;38(3):507-510. 10.3348/jkrs.1998.38.3.507.

MRI Findings of Extramedullary Hematopoiesis of the Spleen in Patient with Idiopathic Myelofibrosis: 2 case report

• Kim HS
• Park CM
• Cha IH
• Kim A
• Lee MG
• Auh YH

• KMID: 2201410
• DOI: http://doi.org/10.3348/jkrs.1998.38.3.507

Abstract

MRI findings of extramedullary hematopoiesis of the spleen have not been described in the literature. Wereport the MRI features of this condition, as seen in two patients and confirmed by fine needle biopsy. Threesmall masses(< or =3cm) were isointense on T1WI, hyperintense on T2WI, and enhanced after the injection of gadolinium.Two 6cm-sized masses were hypointense on both T1WI and T2WI, and showed no contrast enhancement.

Keyword

Spleen, MR; Spleen, diseases

MeSH Terms

Biopsy, Fine-Needle
Hematopoiesis, Extramedullary*
Humans
Magnetic Resonance Imaging*
Primary Myelofibrosis*
Spleen*

Figure

• 

  Fig. 1. Extramedullary hematopoiesis of the spleen in 38-year-old man with myelofibrosis. A. Tl-weighted image (TR/TE, 600msec/l7 msec) shows a 6cm sized, slightly low signal intensity lesion(arrows), in the lower pole of enlarged spleen. B. Same lesion in the lower pole is noted as low signal intensity on T2-weighted image (TR/tE, 3300msec/140msec). C. T2-weighted image (TR/TE, 3300msec/140msec) shows two lesions of high signal intensity with diameters less than 3cm in the upper pole of spleen. Another small lesion of high signal intensity was also noted (not shown). D. Post-Gadolinium enhanced Tl-weighted image (TR/TE, 600msec/l7msec) shows contrast enhancement of the upper pole lesions. Lower pole lesion was not enhanced (not shown).

• 

  Fig. 2. Extramedullary hematopoiesis of the spleen in 69-year-old man with myelofibrosis. A. Tl-weighted image (TR/TE, 500msec/20mse) shows 6cm-sized focal lesion of low signal intensity. B. This lesion is demonstrated as low signal intensity on Τ2-weighted image (TR/TE, 2000msec/80msec).

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