J Korean Radiol Soc.  2000 Aug;43(2):245-250. 10.3348/jkrs.2000.43.2.245.

Results with Add-on Stereotactic Core Biopsy (ASCB)of the Breast Lesions

Affiliations
  • 1Department of Radiology, University of Ulsan, Asan Medical Center.
  • 2Department of Pathology, University of Ulsan, Asan Medical Center.
  • 3Department of Surgery, University of Ulsan, Asan Medical Center.

Abstract

PURPOSE: To report the results of 134 cases in which add-on stereotactic core biopsy (ASCB) was performed in patients with mammographically detected breast lesions, and to evaluate the usefulness of this procedure.
MATERIALS AND METHODS
We analyzed the results of ASCB of 134 breast lesions in 125 patients, performed during a 41-month period. The mammographic findings were suspicious malignant lesion in 38 cases, benign lesion in 18, and indeterminate lesion in 78. Surgical excision was performed in 23 cases, and follow-up mammography in 39. We analyzed the pathologic results according to each mammographic finding and correlated the results of core biopsy with those of surgical excision. We also evaluated the mammographic changes seen during follow-up, and associated complications and procedural difficulties.
RESULTS
Samples were adequate for pathologic diagnosis in 95% of cases (127/134). ASCB revealed malignancy in 47% of cases (18/38) in which this was suspected on the basis of mammographic findings, and in 5% of cases (4/78) in which these findings were indeterminate. The pathologic results of core biopsy and of surgical excision agreed in 78% of cases (18/23). In two of five false-negative cases, ASCB revealed the presence of atypical ductal hyperplasia. The mammographic findings in these five cases were suspicious malignancy in three, and indeterminate in two. Specimen radiography showed calcifications in four cases. The size or extent of mammographic lesions did not change during the mean follow-up period of 17.3 months. In 13/125 patients (10%), the complications and procedural difficulties noted included arterial bleeding, dizziness, syncope, patient movement, and instrument failure.
CONCLUSION
ASCB is accurate, safe and useful, but surgical excision should be considered when the ASCB result is either atypical ductal hyperplasia or benign but with mammographic diagnosis of suspicious malignant or indeterminate lesions.

Keyword

Breast, biopsy; Breast neoplasms, diagnosis

MeSH Terms

Biopsy*
Breast*
Diagnosis
Dizziness
Follow-Up Studies
Hemorrhage
Humans
Hyperplasia
Mammography
Radiography
Syncope
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