J Korean Pain Soc.  1991 Jun;4(1):60-63.

Neuroleptic Malignant Syndrome after Epidural Administration of Droperidol

• Ahn MJ
• Suh JH
• Kim SN

Abstract

The neuroleptic malignant syndrome (NMS) is an uncommon but dangerous complication of treatment with neuroleptic drugs. This syndrome is characterized by autonomic dysfunction, extrapyramidal dysfunction, and hyperthermia. NMS seems more frequent with parentral neuroleptic use. We report a patient in whom suspicious NMS was developed in the ward after epidural administration of 2. 5mg of droperidol with morphine for postoperative pain control. Extrapyramidal symptoms and autonomic dysfunction were treated with diazepam, but temperature was spontaneously deereased after l6 hours and 40 minute after receiving epidural droperidol.

MeSH Terms

Antipsychotic Agents
Diazepam
Droperidol*
Fever
Humans
Morphine
Neuroleptic Malignant Syndrome*
Pain, Postoperative
Antipsychotic Agents
Diazepam
Droperidol
Morphine