J Korean Soc Ther Radiol.  1991 Jun;9(1):53-58.

The Effect of External Radiation Therapy for Intracranial Arteriovenous Malformation: Conventional Radiation Therapy vs Stereotactic Radiosurgery

• Kim IA
• Jang HS
• You MR
• Yoon SC
• Kim MC
• Shinn KS
• Bahk YW

Abstract

From February 1987 through July 1990, the seventeen cases of inoperabelintracranial arteriovenous malformation (AVM) were treated using 6 MV linear accelerator at the Division of Therapeutic Radiology, Kang Nam St. Mary's Hospital. Of seventeen cases, fourteen were male and three were female. Ages ranged from 10 to 51 years (median age of 26 years). The main symptoms were headache, epilepsy and hemiparesis in decreasing order of frequency. The middle cerebral artery is the most common origin of the feeding vessel (41.2%). Four were treated by conventionally fractionated radiation therapy (CRT), thirteen were treated by stereotactic radiosurgery (RS). Duration of follow-up study, two of four CRT group showed minimal response. Of thirteen cases of RS group, two (15.4%) showed complete response, five (38%) partial response, two (15.4%) minimal response and four (30.7%) no response by the same assessment. There was no statistical significance in terms of follow-up period (p=0.22), size of lesion (p=0.82) and treated dose (p=0.65). Further accumulation of experience s recommended with proper case selection and sufficient follow-up period.

Keyword

Arteriovenous malformation; Linear accelerator; Sterotactic radiosurgery; Conventional radiation therapy

MeSH Terms

Arteriovenous Malformations
Epilepsy
Female
Follow-Up Studies
Headache
Humans
Intracranial Arteriovenous Malformations*
Male
Middle Cerebral Artery
Paresis
Particle Accelerators
Radiation Oncology
Radiosurgery*