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Feasibility and efficacy of coil embolization for middle cerebral artery aneurysms

Choi JY, Choi CH, Ko JK, Lee JI, Huh CW, Lee TH

BACKGROUND: The anatomy of middle cerebral artery (MCA) aneurysms has been noted to be unfavorable for endovascular treatment. The purpose of this study was to assess the feasibility and efficacy...
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Effects of Recumbent Angle during Cycling on Cerebral Blood Flow Velocity and Rate Pressure Product during Exercise and Recovery

Kim SD, Jeong IG, Koh YS, Lee HH

BACKGROUND: The cerebral blood flow velocity (CBFV) and rate pressure product (RPP) have been reported to benefit hemodynamics more during exercise in the recumbent position than during that in the...
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Endovascular Thrombectomy for Distal Occlusion Using a Semi-Deployed Stentriever: Report of 2 Cases and Technical Note

Wan Y, Yang IH, Orru E, Krings T, Tsang AC

Distal intracranial occlusions can sometimes cause significant neurological deficits. Endovascular thrombectomy in these vessels may improve outcome but carry a higher risk of haemorrhagic complications due to the small calibre...
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De Novo Intracranial Aneurysms Detected on Imaging Follow-Up of Coiled Aneurysms in a Korean Population

Yeon EK, Cho YD, Yoo DH, Lee SH, Kang HS, Cho WS, Kim JE, Han MH

OBJECTIVE: Coiled aneurysms are known to recanalize over time, making follow-up evaluations mandatory. Although de novo intracranial aneurysms (DNIAs) are occasionally detected during routine patient monitoring, such events have not...
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Increased CD68/TGFβ Co-expressing Microglia/Macrophages after Transient Middle Cerebral Artery Occlusion in Rhesus Monkeys

Yeo HG, Hong JJ, Lee Y, Yi KS, Jeon CY, Park J, Won J, Seo J, Ahn YJ, Kim K, Baek SH, Hwang EH, Kim G, Jin YB, Jeong KJ, Koo BS, Kang P, Lim KS, Kim SU, Huh JW, Kim YH, Son Y, Kim JS, Choi CH, Cha SH, Lee SR

The function of microglia/macrophages after ischemic stroke is poorly understood. This study examines the role of microglia/macrophages in the focal infarct area after transient middle cerebral artery occlusion (MCAO) in...
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Primary neurocritical care involving therapeutic hypothermia for acute ischemic stroke patients with malignant infarct cores

Lee SJ, Lee KS, Lee JS, Choi MH, Lee SE, Hong JM

BACKGROUND: Acute ischemic stroke patients with malignant infarct cores were primarily treated with neurocritical care based on reperfusion and hypothermia. We evaluated the predictors for malignant progression and functional outcomes. METHODS:...
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Arterial Spin Labeling MRI for Quantitative Assessment of Cerebral Perfusion Before and After Cerebral Revascularization in Children with Moyamoya Disease

Ha JY, Choi YH, Lee S, Cho YJ, Cheon JE, Kim IO, Kim WS

OBJECTIVE: To determine the correlation between cerebral blood flow (CBF) on arterial spin labeling (ASL) MRI and the degree of postoperative revascularization assessed on digital subtraction angiography in children with...
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Association Between Duration of Dysphagia Recovery and Lesion Location on Magnetic Resonance Imaging in Patients With Middle Cerebral Artery Infarction

Kim JH, Oh SH, Jeong HJ, Sim YJ, Kim DG, Kim GC

OBJECTIVE: To investigate association between lesion location on magnetic resonance imaging (MRI) performed after an infarction and the duration of dysphagia in middle cerebral artery (MCA) infarction. METHODS: A videofluoroscopic swallowing...
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Pseudo-Subarachnoid Hemorrhage; Chronic Subdural Hematoma with an Unruptured Aneurysm Mistaken for Subarachnoid Hemorrhage

Son D, Kim Y, Kim C, Lee S

Subarachnoid hemorrhage (SAH) usually occurs due to aneurysmal rupture of intracranial arteries and its typical computed tomography (CT) findings are increased attenuation of cisterns and subarachnoid spaces. However, several CT...
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Effects of Bicycle Ergometer Exercise on Cerebral Blood Flow Velocity and Electroencephalogram Response in Normoxia and Hypoxia

Kim SD, Kim MW, Jeong IG

BACKGROUND: The cerebral blood flow velocity (CBFV) has been known to increase in response to acute hypoxia. However, how CBFV might respond to exercise in hypoxic conditions and be associated...
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Efficacy and Safety of Endovascular Treatment in Patients with Internal Carotid Artery Occlusion and Collateral Middle Cerebral Artery Flow

Kim YW, Kang DH, Kim YS, Hwang YH

OBJECTIVE: In patients with internal carotid artery (ICA) occlusion, collateral middle cerebral artery (MCA) flow has a protective role against ischemia. However, some of these patients may experience initial major...
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Meta-Analysis of Endovascular Treatment for Acute M2 Occlusion

Kim CH, Kim SE, Jeon JP

OBJECTIVE: Endovascular treatment (EVT) outcomes for acute M2 segment of middle cerebral artery occlusion remains unclear because most results are obtained from patients with large artery occlusion in the anterior...
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Traumatic Rupture of the Middle Cerebral Artery Followed by Acute Basal Subarachnoid Hemorrhage: Tailored Approach in Forensic Pathology by Aid of Post-mortem Angiographic Findings

Park S, Lee S, Yang KM, Kim D, Lee H, Cha JG

We present the case of a 23-year-old man who suddenly collapsed during a physical altercation with his friends while in a drunken state. The post-mortem computed tomography (CT) with angiography...
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Intraarterial therapy for middle cerebral artery dissection with intramural hematoma detection on susceptibility-weighted imaging

Yoon C, Jung S, Jeong H, Cho E, Yang TW, Kim SJ, Park KJ, Kim SS, Park H

BACKGROUND: Intracranial artery dissection (IAD) may be an underdiagnosed cause of large vessel occlusion. The safety and efficacy of intra-arterial therapy (IAT) in patients with IAD are largely unknown. We...
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Platycarya strobilacea leaf extract protects mice brain with focal cerebral ischemia by antioxidative property

Lee JH, Jeong JH, Jeong YG, Kim DK, Lee NS, Na CS, Doh ES, Han SY

The leaf extract of Platycarya strobilacea (PSL) has long been recognized as possessing various health-promoting activities. However, information on its possible protective effects against ischemic stroke is currently lacking. Here,...
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Characteristics and Clinical Course of Fusiform Middle Cerebral Artery Aneurysms According to Location, Size, and Configuration

Seo D, Lee SU, Oh CW, Kwon OK, Ban SP, Kim T, Byoun HS, Kim YD, Lee Y, Won YD, Bang JS

OBJECTIVE: To analyze the angiographic features and clinical course, including treatment outcomes and the natural course, of fusiform middle cerebral artery aneurysms (FMCAAs) according to their location, size, and configuration. METHODS:...
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S1P₁ Regulates M1/M2 Polarization toward Brain Injury after Transient Focal Cerebral Ischemia

Gaire BP, Bae YJ, Choi JW

M1/M2 polarization of immune cells including microglia has been well characterized. It mediates detrimental or beneficial roles in neuroinflammatory disorders including cerebral ischemia. We have previously found that sphingosine 1-phospate...
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Resveratrol modulates the Akt/GSK-3β signaling pathway in a middle cerebral artery occlusion animal model

Park DJ, Kang JB, Shah FA, Koh PO

Cerebral ischemia is a major cause of neurodegenerative disease. It induces neuronal vulnerability and susceptibility, and leads to neuronal cell death. Resveratrol is a polyphenolic compound that acts as an...
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Estimation of Acute Infarct Volume with Reference Maps: A Simple Visual Tool for Decision Making in Thrombectomy Cases

Kim DE, Ryu WS, Schellingerhout D, Jeong H, Kim P, Jeong SW, Park MS, Choi KH, Kim JT, Kim BJ, Han MK, Lee J, Cha JK, Kim DH, Nah HW, Lee SJ, Kim JG, Hong KS, Cho YJ, Park HK, Lee BC, Yu KH, Oh MS, Park JM, Kang K, Lee KB, Park TH, Park SS, Lee YS, Bae HJ

BACKGROUND AND PURPOSE: Thrombectomy within 24 hours can improve outcomes in selected patients with a clinical-infarct mismatch. We devised an easy-to-use visual estimation tool that allows infarct volume estimation in...
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Correlation of Adventitial Vasa Vasorum with Intracranial Atherosclerosis: A Postmortem Study

Zheng L, Yang WJ, Niu CB, Zhao HL, Wong KS, Leung TW, Chen XY

BACKGROUND AND PURPOSE: Vasa vasorum (VV) have been believed to be rare or non-existent in small-caliber intracranial arteries. In a series of human cerebral artery specimens, we identified and examined...
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