J Korean Soc Pediatr Nephrol.  2014 Apr;18(1):13-17.

Continuous Renal Replacement Therapy in Infants and Neonates

Affiliations
  • 1Department of Pediatrics, Pusan National University Children's Hospital, Pusan National School of Medicine, Yangsan, Korea.
  • 2Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, Korea. shinji@yuhs.ac

Abstract

Continuous renal replacement therapy (CRRT) has become the preferred dialysis modality to support critically ill children with acute kidney injury. As CRRT technology and clinical practice advances, experiences using CRRT on small infants and neonates have increased. In neonates with hyperammonemia or acute kidney injury during extracorporeal membrane oxygenation (ECMO) therapy, CRRT can be a safe and effective technique. However, there are many limitations of CRRT in neonates, including vascular access, bleeding complications, and lack of neonate-specific devices. This review discusses the basic principles of CRRT and the special considerations when using this technique in neonates and infants.

Keyword

Continuous renal replacement therapy (CRRT); Neonate and Infant
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