J Korean Orthop Assoc.  2008 Jun;43(3):374-378. 10.4055/jkoa.2008.43.3.374.

Calcific Amyloidoma of Tibialis Anterior Muscle: Case Report

• Cho BK
• Kim YM
• Kim DS
• Choi ES
• Shon HC
• Park KJ
• Cui HS
• Kim SW
• Lee OJ

• KMID: 2186455
• DOI: http://doi.org/10.4055/jkoa.2008.43.3.374

Abstract

Calcific amyloidoma of the soft tissue is quite rare and it is difficult to make a differential diagnosis from other lesions such as osteomyelitis or bone tumor. We encountered a case of a calcified amyloidoma found in the anterior tibial muscle that occurred more than 20 years after a proximal tibial fracture adjacent to the origin of the muscle. The features of the lesion resembled osteomyelitis. Satisfactory result was obtained by a thorough mass excision. We report this case with review of the relevant literature.

Keyword

Amyloidoma; Calcification; Anterior tibial muscle; Fracture

MeSH Terms

Diagnosis, Differential
Muscle, Skeletal
Muscles
Osteomyelitis
Tibial Fractures

Figure

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  Fig. 1 There were a large amount of high density streaky sclerotic lesions over almost the whole space of the tibialis anterior muscle. An old fracture of the proximal tibia was observed with complete union.

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  Fig. 2 The sclerotic mass on the plain X-ray was observed as low signal intensity (white arrow) on the T2-weighted axial (A) and sagittal (B) MR images. Overlying subcutaneous tissue showed high signal changes (dark arrow head) suggesting fluid collection.

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  Fig. 3 There were a large amount of sawdust like osseous components around the interosseous membrane, which were scattered in the anterior side of the right tibia.

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  Fig. 4 The lesion appeared as an amorphous, eosinophilic, hyaline, extracellular substance with calcification (A: HE, ×100). Under polarized light, the Congo red-stained amyloid in the tissue showed green birefringence (B, ×100).

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