J Korean Acad Rehabil Med.  2006 Oct;30(5):424-429.

Factors Affecting Drooling in Adult Patients with Traumatic Brain Injury

Affiliations
  • 1Department of Rehabilitation Medicine, Ewha Womans University College of Medicine, Korea.
  • 2Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Korea. imdrnam@dreamwiz.com

Abstract


OBJECTIVE
To investigate whether drooling in patients with traumatic brain injury (TBI) is due to hypersalivation or cognitive dysfunction or disability. METHOD: The subjects were 24 TBI patients with drooling and 17 TBI patients without drooling and 20 unaffected healthy volunteers who had no known physical or mental disabilities. All participants had no known history of diabetes mellitus, hypertension, thyroid dysfunction or chronic alcoholism. And, we excluded the subjects who take the anticholinergics, beta-agonist or steroid. Salivary pH and flow rate were compared between the TBI groups and the control group. We also measured Korean mini-mental state examination (K-MMSE) and disability rating scale (DRS) and compared mean values between TBI groups.
RESULTS
There was no statistical difference in the mean salivary pH and flow rate between the tested groups. The drooling severity and frequency showed no correlation with salivary flow rate in all groups. The drooling severity and frequency showed significant correlations with K-MMSE, but not with DRS in TBI groups.
CONCLUSION
The results of this study suggested that the cause of drooling in patients with TBI may not be the hypersalivation and functional disability, but cognitive dysfunction.

Keyword

Traumatic brain injury; Drooling; Salivary flow rate; Cognition

MeSH Terms

Adult*
Alcoholism
Brain Injuries*
Cholinergic Antagonists
Cognition
Diabetes Mellitus
Healthy Volunteers
Humans
Hydrogen-Ion Concentration
Hypertension
Sialorrhea*
Thyroid Gland
Cholinergic Antagonists
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