J Korean Diabetes Assoc.  1999 Feb;23(1):70-78.

Prevalence of Insulin Resistance Syndrome in Subjects Living in Jungup District , Korea

• Kim SW
• Kim JY
• Kim ES
• Kim YI
• Lee MS
• Kim HH
• Park JY
• Hong SK
• Lee KU

Abstract

BACKGROUND: The clustering of hypertension, impaired glucose tolerance, low HDL cholesteml and high triglyceride is known as insulin resistance syndrome (IRS). We studied the prevalence of insulin resistance syndrome among subjects living in Jungup district, Korea.
METHODS
Among a total of 151,000 subjects over 40 years of years living in Jungup district, a sample of 1,791 was selected using a random cluster sampling method. Oral glucose tolerance test revealed 1,018 subjects with normal or impaired glucose tolerance. The IRS was defined as the coexistence of two or more components of triad; hypertension, impaired glucose tolerance and dyslipidemia (triglycerides >= 200mg/dL and HDL <45 mg/dL for woman, HDL < 35 mg/dL for men). RESULTS: Twenty-one percent of men and 45% of women were obese and 50.8% and 61.9% were hypertensive. Eleven percent of men and 16 percent of women were found to have dyslipidemia. The prevalence of impaired glucose tolerance was 10.2% for men and 15.7% for women. The prevalence of IRS in the Jungup population was 12.8% for men and 19.6% for women. The prevalence of IRS increased according to the plasma level of insulin. There was a positive correlation between the number of components of IRS and the level of fasting plasma insulin.
CONCLUSION
We conclude that the prevalence of IRS is high in Korean subjects. The close correlation between the IRS components and fasting insulin level suggests that cardiovascular risk is associated with insulin resistance.

Keyword

Prevalence; Insulin resistance syndrome; Hyperinsulinemia

MeSH Terms

Dyslipidemias
Fasting
Female
Glucose
Glucose Tolerance Test
Humans
Hyperinsulinism
Hypertension
Insulin Resistance*
Insulin*
Jeollabuk-do*
Korea*
Male
Plasma
Prevalence*
Triglycerides
Glucose
Insulin