J Korean Endocr Soc.  2010 Mar;25(1):46-49. 10.3803/jkes.2010.25.1.46.

A Case of Follicular Thyroid Carcinoma Associated with Hemiagenesis of Thyroid Gland

• Kim BK
• Jung HJ
• Kim YN
• Choi YS
• Park YH
• Chang HK
• Kim JH

• KMID: 2177860
• DOI: http://doi.org/10.3803/jkes.2010.25.1.46

Abstract

Thyroid hemiagenesis is a rare congenital anomaly, in which one thyroid lobe fails to develop. Thyroid hemiagenesis is associated with thyroid diseases such as Graves' disease, Hashimoto's thyroiditis, colloidal goiter and thyroid follicular and papillary cancer. A 53-year-old female patient was diagnosed with a thyroid nodule on health examination. A 99mTc pertechnetate thyroid scan showed absent uptake in the left lobe and cold nodule on the right lobe of thyroid gland. By ultrasonography, we found hemiagenesis in the left thyroid gland and an irregular shaped thyroid nodule on the right lobe of thyroid gland. We performed ultrasonography guided fine needle aspiration and cytologic analysis showed indeterminate nature. Thyroidectomy was performed and finally diagnosed follicular carcinoma of thyroid gland. The authors report this case with a literature review.

Keyword

Follicular cancer; Thyroid hemiagenesis

MeSH Terms

Adenocarcinoma, Follicular
Biopsy, Fine-Needle
Cold Temperature
Colloids
Female
Goiter
Graves Disease
Humans
Middle Aged
Sodium Pertechnetate Tc 99m
Thyroid Diseases
Thyroid Gland
Thyroid Nodule
Thyroidectomy
Thyroiditis
Colloids
Sodium Pertechnetate Tc 99m

Figure

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  Fig. 1 Ultrasound examination of the thyroid gland in transverse section: Visualization of the right lobe with a hypoechogenic nodule with calcified and irregular margin whereas thyroid tissue on the left side is not observed.

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  Fig. 2 Absence of 99mTc in pertechnate uptake in left lobe that is compatible with thyroid hemiagenesis. A hypoechoic nodule is also seen in the right lobe of thyroid.

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  Fig. 3 A. The microscopic finding shows tumor; follicular neoplasm invasion of severely calcified capsule (H&E stain, ×40), B. The microscopic finding shows tumor of angioinvasion (H&E stain, ×100).

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