Blood Res.  2013 Jun;48(2):156-160. 10.5045/br.2013.48.2.156.

EBV-positive diffuse large B-cell lymphoma of the elderly with aberrant expression of CD3 and TIA-1

• Lee M
• Cha HJ
• Yoon DH
• Suh C
• Huh J

• KMID: 2172919
• DOI: http://doi.org/10.5045/br.2013.48.2.156

Abstract

No abstract available.

MeSH Terms

Aged
B-Lymphocytes
Humans
Lymphoma, B-Cell

Figure

• 

  Fig. 1 (A) Pleomorphic large tumor cells with prominent nucleoli, vesicular chromatin, and scanty cytoplasm are admixed with small numbers of mature lymphocytes. (B) A positive in situ hybridization for EBER in tumor cell nuclei is seen. (C-E) The neoplastic cells are diffusely and strongly positive for the T-cell marker CD3 (C), the B-cell marker CD20 (D), and the cytotoxic molecule TIA-1 (E) (A-E, ×400).

• 

  Fig. 2 This tumor demonstrates dual rearrangement (red arrows) of IgH genes (A) and TCR-γ genes (B) by multiplex PCR.

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